Unni N M, Mandalam K R, Rao V R, Gupta A K, Joseph S, Rao A S, Unnikrishnan M, Neelakandhan K S
Sree Chitra Tirunal Institute of Medical Sciences and Technology, Kerala, India.
Natl Med J India. 1995 May-Jun;8(3):105-13.
Disease of the femoral and popliteal arteries, though one of the commonest manifestations of atherosclerosis, is under-recognized because the morbidity it produces is less catastrophic than coronary or cerebrovascular arterial involvement. Percutaneous transluminal angioplasty is performed for femoro-popliteal lesions at different centres in India, but post-angioplasty follow up data are scarce. We present our results after femoro-popliteal balloon angioplasty in 140 lesions.
Between 1986 and 1993, 140 femoro-popliteal angioplasties were performed in 119 patients with symptomatic limb ischaemia. Seventy-one per cent of patients had claudication and the others also had tissue loss. Eighty-two per cent of the lesions were occlusions. The average length of the lesions was 10.7 cm. Conventional wire-balloon angioplasty was performed in 128 lesions; in 12 others, laser-assisted balloon angioplasty was performed using an Nd-YAG laser thermal probe. Patients were followed up at regular intervals for any recurrence of symptoms and for objective evidence of restenosis or re-occlusion.
Despite a technical success in 83% of the lesions, cumulative primary patency calculated by the life-table method showed a slow decline which plateaued at 40% after 36 months. Long occlusions and multifocal stenoses showed shorter cumulative patency following angioplasty (27 months and 5.8 months respectively). Extensive luminal irregularity due to post-angioplasty intimal flaps was reduced by using warm contrast for balloon dilatation in 16 patients. In 14 patients who had repeat angioplasty for restenosis, the secondary patency showed a satisfactory figure of 84% at 60 months.
Percutaneous transluminal angioplasty is a satisfactory alternative to surgery in femoro-popliteal stenotic or occlusive disease. Regular follow up of such patients is essential in the first three years because re-occlusion can occur. We found that patency remained fairly constant after 36 months. Repeated angioplasty can maintain patency in patients with restenosis.
股动脉和腘动脉疾病虽是动脉粥样硬化最常见的表现之一,但因它所导致的发病率不像冠状动脉或脑血管动脉受累那样具有灾难性,所以未得到充分认识。在印度的不同中心,均对股腘病变进行经皮腔内血管成形术,但血管成形术后的随访数据却很匮乏。我们展示了对140处病变进行股腘球囊血管成形术后的结果。
1986年至1993年间,对119例有症状性肢体缺血的患者进行了140次股腘血管成形术。71%的患者有间歇性跛行,其他患者也有组织缺失。82%的病变为闭塞性病变。病变的平均长度为10.7厘米。128处病变采用传统的导丝球囊血管成形术;另外12处病变使用钕钇铝石榴石激光热探头进行激光辅助球囊血管成形术。定期对患者进行随访,观察症状是否复发以及是否有再狭窄或再闭塞的客观证据。
尽管83%的病变在技术上取得成功,但采用寿命表法计算的累积原发性通畅率呈缓慢下降趋势,36个月后稳定在40%。长段闭塞和多灶性狭窄在血管成形术后的累积通畅时间较短(分别为27个月和5.8个月)。通过对16例患者在球囊扩张时使用温热造影剂,减少了血管成形术后内膜瓣导致的广泛管腔不规则。在14例因再狭窄而接受再次血管成形术的患者中,二次通畅率在60个月时达到了令人满意的84%。
经皮腔内血管成形术是治疗股腘狭窄或闭塞性疾病的一种令人满意的手术替代方法。对这类患者在前三年进行定期随访至关重要,因为可能会发生再闭塞。我们发现36个月后通畅率保持相当稳定。再次血管成形术可维持再狭窄患者的通畅。