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对于已有根管充填的牙齿,应采用手术治疗还是非手术治疗?

Surgical or nonsurgical treatment for teeth with existing root filings?

作者信息

Naito Toru

机构信息

Department of Geriatric Dentistry , Fukuoka Dental College, Tamura 2-15-1, Sawara, Fukuoka, Japan.

出版信息

Evid Based Dent. 2010;11(2):54-5. doi: 10.1038/sj.ebd.6400724.

Abstract

DATA SOURCES

Data was sought using Medline and the Cochrane Library, and relevant chapters from three major endodontic texts were consulted: Principles and Practice of Endodontics (4th Edn; editors; Torabinejad and Walton; 2008); Pathways of the Pulp (9th edition; editors, Cohen and Hargreaves; 2006), and Endodontics (6th edition; editors, Ingle, Bakland and Baumgartner; 2008). Every issue was also searched of the most recent 2 years of the following major endodontic journals: International Endodontic Journal; Journal of Endodontics; and Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology along with the reference lists of identified articles.

STUDY SELECTION

Articles were included from peer-reviewed journals if they were published in English, and reported clinical and/or radiographic outcome data for nonsurgical endodontic retreatment or for endodontic surgery, with followup data for a minimum of 25 teeth and a minimum 2-year mean followup period. Studies reporting outcomes based on individual roots as opposed to whole teeth, or that did not report clinical or radiographic outcomes, which were animal studies, or studies that reported histological data only, were excluded.

DATA EXTRACTION AND SYNTHESIS

When necessary, the reviewers recalculated success and failure rates when they were not directly provided in papers' tables or in the text, or when only particular data subsets met the inclusion criteria. To facilitate meta-analysis, the data were standardised according to a commonly applied classification system used to assess outcomes for nonsurgical retreatment and surgical endodontics: (1) Complete healing; (2) Incomplete healing; (3) Uncertain healing; and (4) Unsatisfactory healing (failures). When uncertainty existed regarding which of the above four categories correlated with those reported in a given article, the data were assigned to the lower healing category. For this review, success was defined as teeth categorised as showing complete healing or incomplete healing. Weighted success rates, pooled success rates, and 95% confidence interval (CI) estimates of outcomes were generated in the metaanalysis from compiled data from the included studies by using the DerSimonian-Laird random effects pooling method.

RESULTS

Twenty-six endodontic surgery and eight nonsurgical retreatment articles were included. There were only four randomised controlled trials (one in the nonsurgical retreatment, and three in the endodontic surgery group). A significantly higher success rate was found for endodontic surgery at 2-4 years (77.8%) than for nonsurgical retreatment for the same followup period (70.9%; P <0.05). At 4-6 years, however, this relationship was reversed, with nonsurgical retreatment showing a higher success rate of 83.0%, compared with 71.8% for endodontic surgery (P <0.05). Insufficient numbers of articles were available to make comparisons after 6 years of followup. Endodontic surgery studies showed a statistically significant decrease in success with each increasing followup interval (P <0.05). The weighted success for 2-4 years was 77.8%, which declined at 4-6 years to 71.8% and further declined at >6 years to 62.9% (P <0.05). Conversely, the nonsurgical retreatment success rates demonstrated a statistically significant increase in weighted success at 2-4 years (70.9%) versus 4-6 years (83.0%; P <0.05).

CONCLUSIONS

On the basis of these results it appears that endodontic surgery offers more favourable initial success, but nonsurgical retreatment offers a more favourable long-term outcome.

摘要

数据来源

通过医学文献数据库(Medline)和考科蓝图书馆检索数据,并查阅了三本主要牙髓病学教科书的相关章节:《牙髓病学原理与实践》(第4版;编者:托拉比内贾德和沃尔顿;2008年);《牙髓病学路径》(第9版;编者:科恩和哈格里夫斯;2006年)以及《牙髓病学》(第6版;编者:英格尔、巴克兰和鲍姆加特纳;2008年)。还检索了以下主要牙髓病学期刊最近两年的每一期:《国际牙髓病学杂志》;《牙髓病学杂志》;以及《口腔外科、口腔医学、口腔病理学、口腔放射学和牙髓病学》,同时查阅了已识别文章的参考文献列表。

研究选择

纳入同行评审期刊发表的英文文章,这些文章报告了非手术牙髓再治疗或牙髓手术的临床和/或影像学结果数据,且随访数据至少涉及25颗牙齿,平均随访期至少2年。报告基于单个牙根而非整颗牙齿的结果的研究,或未报告临床或影像学结果的研究、动物研究或仅报告组织学数据的研究均被排除。

数据提取与综合

必要时,若论文表格或正文未直接提供成功率和失败率,或只有特定数据子集符合纳入标准,评审人员会重新计算成功率和失败率。为便于进行荟萃分析,数据根据一种常用的分类系统进行标准化,该系统用于评估非手术再治疗和牙髓手术的结果:(1)完全愈合;(2)不完全愈合;(3)愈合情况不确定;(4)愈合不满意(失败)。当对于给定文章中报告的结果与上述四类中的哪一类相关存在不确定性时,数据被归入较低的愈合类别。对于本综述,成功定义为归类为显示完全愈合或不完全愈合的牙齿。在荟萃分析中,使用DerSimonian-Laird随机效应合并方法,根据纳入研究的汇总数据生成结果的加权成功率、合并成功率和95%置信区间(CI)估计值。

结果

纳入了26篇牙髓手术和8篇非手术再治疗的文章。仅有4项随机对照试验(1项在非手术再治疗组,3项在牙髓手术组)。发现牙髓手术在术后2至4年的成功率(77.8%)显著高于同期非手术再治疗的成功率(70.9%;P<0.05)。然而,在术后4至6年,这种关系发生了逆转,非手术再治疗的成功率更高,为83.0%,而牙髓手术为71.8%(P<0.05)。随访6年后可用于比较的文章数量不足。牙髓手术研究显示,随着随访间隔的增加,成功率在统计学上显著降低(P<0.05)。2至4年的加权成功率为77.8%,在4至6年降至71.8%,在超过6年时进一步降至62.9%(P<0.05)。相反,非手术再治疗的成功率在2至4年(70.9%)与4至6年(83.0%)之间的加权成功率在统计学上有显著提高(P<0.05)。

结论

基于这些结果,似乎牙髓手术在初始阶段成功率更高,但非手术再治疗的长期效果更好。

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