[胃癌D（2）切除术后胰瘘的危险因素]
[Risk factors for postoperative pancreatic leakage after D(2) resection of gastric cancer].
作者信息
Chen Wei-dong, Liu Feng-lin, Shen Zhen-bin, Shen Kun-tang, Sun Yi-hong, Qin Jing, Qin Xin-yu
机构信息
Department of General Surgery, Zhongshan Hospital, Fudan University, Fudan University General Surgery Institute, Shanghai 200032, China.
出版信息
Zhonghua Wei Chang Wai Ke Za Zhi. 2010 Jun;13(6):421-3.
OBJECTIVE
To investigate the incidence of pancreatic fistula following D(2) gastrectomy and associated risk factors.
METHODS
A total of 132 consecutive cases of gastric cancer underwent D(2) gastrectomy between Jul 1, 2009 and Dec 2009. Amylase concentration of the drainage fluid and serum amylase concentration were tested on day 1, 4, 7 after operation. Univariate analyses were performed to evaluate the significance of various covariates as risk factors for the pancreatic fistula-related complications.
RESULTS
The incidence of pancreatic fistula was 17.4%. None of the following factors including age, gender, tumor location, tumor stage, N stage, range of resection, fistula output, and serum amylase were associated with pancreatic fistula.
CONCLUSION
The incidence of pancreatic fistula following D(2) gastrectomy is high. Drainage tube is necessary to prevent serious complications.
目的
探讨D（2）胃切除术后胰瘘的发生率及相关危险因素。
方法
2009年7月1日至2009年12月期间，共有132例连续的胃癌患者接受了D（2）胃切除术。术后第1、4、7天检测引流液淀粉酶浓度和血清淀粉酶浓度。进行单因素分析以评估各种协变量作为胰瘘相关并发症危险因素的意义。
结果
胰瘘发生率为17.4%。年龄、性别、肿瘤位置、肿瘤分期、N分期、切除范围、瘘液引流量和血清淀粉酶等因素均与胰瘘无关。
结论
D（2）胃切除术后胰瘘发生率较高。放置引流管对于预防严重并发症是必要的。
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