Department of Neurology, University of Virginia Health System, Charlottesville, Virginia 22908-0432, USA.
Semin Neurol. 2010 Jul;30(3):245-53. doi: 10.1055/s-0030-1255221. Epub 2010 Jun 24.
Metastatic epidural spinal cord compression is a debilitating consequence of multiple cancer types. Early diagnosis and treatment are imperative for improving functional outcome. The authors review the epidemiology, pathophysiology, clinical features, and diagnostic evaluation of metastatic epidural spinal cord compression. Special attention will be given to the supportive and definitive treatments available for management, and new therapeutic interventions, such as radiosurgery, will be briefly discussed as well.
转移性硬膜外脊髓压迫是多种癌症类型的一种使人虚弱的后果。早期诊断和治疗对于改善功能预后至关重要。作者回顾了转移性硬膜外脊髓压迫的流行病学、病理生理学、临床特征和诊断评估。将特别关注管理可用的支持性和确定性治疗方法,以及放射外科等新的治疗干预措施也将简要讨论。