Department of Urology, Loma Linda University Medical Center, Loma Linda, California 92354, USA.
J Endourol. 2010 Jul;24(7):1067-72. doi: 10.1089/end.2010.0040.
Although radiation exposure from CT and plain film imaging has been characterized, the radiation received by patients during modern-era fluoroscopy has not been well described. The purposes of this study were to measure absolute organ and tissue-specific radiation doses during ureteroscopy and to determine the influence of body mass index (BMI) and sex on these doses.
Eight cadavers underwent a simulated left ureteroscopy. Using a modern C-arm with automatic exposure control settings, thermoluminescent dosimeters were exposed for a fluoroscopy time of 145 seconds (mean time of clinical ureteroscopies from 2006 to 2008). Total tissue exposures were compared by BMI and between sexes using the Wilcoxon signed ranks test and the Mann-Whitney test with p < 0.05 considered significant.
Among all cadavers, radiation doses were significantly lower in all contralateral organs excluding the gonad (p < 0.012). Doses were similar bilaterally in the gonad in cadavers with BMI <30, and in all organs in cadavers with BMI >30 (p > 0.05). There were significantly higher mean bilateral gonadal doses in female cadavers (3.4 mGy left and 1.9 mGy right) compared with male cadavers (0.36 mGy left and 0.39 mGy right). The highest cancer risk increase was seen at the posterior skin equivalent to 104 additional cancers per 100,000 patients.
Contralateral doses were lower for all organs except the gonad when the BMI was <30. In contrast, when the BMI was >30, there was no difference in radiation dose delivered to the ipsilateral and contralateral organs. Gonadal doses were significantly higher in female cadavers. Modern-era fluoroscopy remains a significant source of radiation exposure and steps should be taken to minimize exposure during ureteroscopy.
虽然已经对 CT 和普通 X 线摄影的辐射暴露进行了描述,但现代透视检查中患者所接受的辐射尚未得到很好的描述。本研究的目的是测量输尿管镜检查期间的绝对器官和组织特异性辐射剂量,并确定体重指数(BMI)和性别对这些剂量的影响。
8 具尸体接受了模拟左输尿管镜检查。使用带有自动曝光控制设置的现代 C 臂,热释光剂量计在透视时间为 145 秒(2006 年至 2008 年期间临床输尿管镜检查的平均时间)下曝光。使用 Wilcoxon 符号秩检验和 Mann-Whitney 检验比较 BMI 之间和性别之间的总组织暴露量,p<0.05 被认为具有统计学意义。
在所有尸体中,除了性腺外,所有对侧器官的辐射剂量均明显较低(p<0.012)。在 BMI<30 的尸体中,性腺的双侧剂量相似,而在 BMI>30 的所有尸体中,所有器官的剂量也相似(p>0.05)。女性尸体的双侧性腺平均剂量明显较高(左侧 3.4 mGy,右侧 1.9 mGy),而男性尸体的双侧性腺平均剂量(左侧 0.36 mGy,右侧 0.39 mGy)较低。最高的癌症风险增加发生在后皮肤等效物,每 100,000 例患者增加 104 例额外癌症。
当 BMI<30 时,除了性腺外,所有器官的对侧剂量均较低。相比之下,当 BMI>30 时,同侧和对侧器官的辐射剂量没有差异。女性尸体的性腺剂量明显较高。现代透视仍然是辐射暴露的重要来源,应采取措施尽量减少输尿管镜检查期间的辐射暴露。