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严重肥胖与输尿管镜检查期间辐射剂量率增加 3 倍相关。

Severe obesity is associated with 3-fold higher radiation dose rate during ureteroscopy.

机构信息

Department of Urology, University of Washington School of Medicine, Seattle, WA.

出版信息

Urology. 2013 Oct;82(4):780-5. doi: 10.1016/j.urology.2013.06.030. Epub 2013 Aug 16.

DOI:10.1016/j.urology.2013.06.030
PMID:23958504
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4843513/
Abstract

OBJECTIVE

To investigate and characterize the association between fluoroscopy radiation dose rate and various patient size metrics during ureteroscopy.

MATERIALS AND METHODS

Fluoroscopy data were collected from 100 patients undergoing ureteroscopy for stone disease. Radiation dose rates were determined from fluoroscopy dose and time. Estimated entrance skin dose was calculated from air kerma (AK) by applying correction factors. Effective dose (ED) was estimated with Monte Carlo-based simulation software. Patient size metrics included body mass index (BMI), anterior-posterior (AP) midline distance, AP transrenal thickness, and region of interest (ROI) pixel value magnitude on computed tomography scout. Univariate and multivariate regression analyses were performed to determine the association between AK dose rate and patient size metrics, adjusting for laterality and stone location.

RESULTS

Obese patients (>30 kg/m(2)) comprised 46% of the cohort. Mean fluoroscopy time, displayed AK, entrance skin dose, and ED were 4.2 ± 6.0 second, 1.2 ± 2.1 mGy, 1.2 ± 2.2 mGy, and 0.08 ± 0.15 mSv, respectively. Mean AK dose rate and ED dose rates were 0.30 ± 0.23 mGy/second and 0.021 ± 0.016 mSv/second, respectively. Compared with the nonobese category, the highest BMI category (≥35 kg/m(2)) had over a 3-fold higher mean AK rate (0.50 vs 0.16 mGy/second). On univariate and multivariate analysis, BMI, AP midline distance, AP transrenal thickness, and computed tomography scout region of interest pixel value magnitude were each significantly associated with dose rate.

CONCLUSION

Larger patients experience higher radiation dose rates under fluoroscopy. Severely obese patients receive 3-fold higher dose rates compared with nonobese patients. Given the higher incidence of stone disease in obese patients, all attempts should be made to minimize radiation exposure during ureteroscopy.

摘要

目的

研究并描述输尿管镜检查过程中透视辐射剂量率与各种患者体型指标之间的关系。

材料与方法

收集了 100 例因结石病而行输尿管镜检查的患者的透视数据。从透视剂量和时间确定辐射剂量率。应用修正因子从空气比释动能(AK)计算估算的皮肤入射剂量。采用基于蒙特卡罗的模拟软件估算有效剂量(ED)。患者体型指标包括体重指数(BMI)、前后(AP)中线距离、AP 经肾厚度和 CT 扫描的感兴趣区(ROI)像素值幅度。进行单变量和多变量回归分析,以确定 AK 剂量率与患者体型指标之间的关系,同时调整侧别和结石位置。

结果

肥胖患者(>30kg/m²)占队列的 46%。平均透视时间、显示 AK、皮肤入射剂量和 ED 分别为 4.2±6.0 秒、1.2±2.1mGy、1.2±2.2mGy 和 0.08±0.15mSv。平均 AK 剂量率和 ED 剂量率分别为 0.30±0.23mGy/秒和 0.021±0.016mSv/秒。与非肥胖组相比,最高 BMI 组(≥35kg/m²)的平均 AK 率高出 3 倍以上(0.50 比 0.16mGy/秒)。在单变量和多变量分析中,BMI、AP 中线距离、AP 经肾厚度和 CT 扫描 ROI 像素值幅度均与剂量率显著相关。

结论

体型较大的患者在透视下接受的辐射剂量率更高。与非肥胖患者相比,肥胖患者的剂量率高出 3 倍。鉴于肥胖患者结石病发病率较高,应尽一切努力在输尿管镜检查期间尽量减少辐射暴露。

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