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迪厄拉富瓦病:大量上消化道出血的罕见病因。

Dieulafoy's lesion: a rare cause of massive upper gastrointestinal haemorrhage.

作者信息

Arora A, Mehrotra R, Patnaik P K, Pande G, Ahlawat S, Bhargava D K

机构信息

Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi.

出版信息

Trop Gastroenterol. 1991 Jan-Mar;12(1):25-30.

PMID:2058007
Abstract

Out of 900 cases of Upper Gastrointestinal haemorrhage seen during 1985-1989, 6 (0.67%) cases had Dieulafoy's lesion as the causative factor. All patients presented with massive upper gastrointestinal haemorrhage. The mean age of the patients was 46.3 year (32-60 yrs) and 4 were males and 2 females. No consistent associated medical factors could be identified. The diagnosis was established by emergency endoscopy which showed an active arterial spurter in 4 patients and located the bleeding site to be close to the fundus in other 2 patients. Injection sclerotherapy tried in 3 patients was not successful. Four patients had bleeding lesion along the greater curvature close to the fundus and two had on posterior wall but all within 6 cm. of gastroesophageal junction. All patients underwent curative emergency surgery with wedge resection of the lesion. We conclude that Dieulafoy lesion should be suspected in a patient with massive, recurrent and obscure upper gastrointestinal bleeding. Emergency endoscopy for diagnosis and prompt surgical intervention can cure the lesion which is potentially fatal if untreated.

摘要

在1985年至1989年间所见的900例上消化道出血病例中,有6例(0.67%)的病因是迪厄拉富瓦病损。所有患者均表现为大量上消化道出血。患者的平均年龄为46.3岁(32至60岁),男性4例,女性2例。未发现一致的相关医学因素。诊断通过急诊内镜检查确定,4例患者显示有活动性动脉喷射出血,另外2例患者的出血部位位于靠近胃底处。对3例患者尝试进行注射硬化疗法,但未成功。4例患者的出血病损位于靠近胃底的大弯侧,2例位于后壁,但均在胃食管交界处6厘米范围内。所有患者均接受了根治性急诊手术,对病损进行楔形切除。我们得出结论,对于大量、复发性和不明原因的上消化道出血患者,应怀疑迪厄拉富瓦病损。通过急诊内镜检查进行诊断并及时进行手术干预可以治愈该病损,若不治疗,该病损可能会致命。

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