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深静脉血栓形成是否是肺栓塞的良好替代标志物?

Is deep vein thrombosis a good proxy for pulmonary embolus?

机构信息

Rothman Institute of Orthopedics at Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA.

出版信息

J Arthroplasty. 2010 Sep;25(6 Suppl):138-44. doi: 10.1016/j.arth.2010.05.001. Epub 2010 Jul 1.

DOI:10.1016/j.arth.2010.05.001
PMID:20580195
Abstract

It is assumed that prevention of deep venous thrombosis (DVT) is likely to lead to a reduction in the incidence of pulmonary embolus (PE). This study examines the association between symptomatic DVT and PE in patients undergoing orthopedic procedures. We reviewed medical records of 1495 patients who underwent evaluation for DVT or PE within 90 days of an index orthopedic procedure at our institution between 2004 and 2008. Only 27 cases were positive for both DVT and PE (1.7% of the total cohort, 10.8% of cases scanned for both DVT and PE). Tests of association, performed across the entire cohort and within specific subsets of patients, did not demonstrate that patients were more likely to have both DVT and PE than to have either DVT or PE. The high association between DVT and PE that is assumed to exist does not seem to hold true for orthopedic surgery patients.

摘要

据推测,预防深静脉血栓(DVT)可能会降低肺栓塞(PE)的发生率。本研究旨在探讨骨科手术患者中症状性 DVT 和 PE 之间的关联。我们回顾了 2004 年至 2008 年间在我院接受骨科手术的 1495 例患者的医疗记录,这些患者在术后 90 天内接受了 DVT 或 PE 的评估。仅 27 例患者同时出现 DVT 和 PE(占总队列的 1.7%,同时扫描 DVT 和 PE 的病例中占 10.8%)。在整个队列和特定亚组患者中进行的关联检验并未表明患者同时出现 DVT 和 PE 的可能性高于仅出现 DVT 或 PE 的可能性。骨科手术患者之间存在的假设性高 DVT 和 PE 关联似乎并不成立。

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