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丹麦与运动相关的心脏性猝死的发生率和病因——对参赛前筛查的影响。

Incidence and etiology of sports-related sudden cardiac death in Denmark--implications for preparticipation screening.

机构信息

Danish National Research Foundation Centre for Cardiac Arrhythmia (DARC), University of Copenhagen, Denmark.

出版信息

Heart Rhythm. 2010 Oct;7(10):1365-71. doi: 10.1016/j.hrthm.2010.05.021. Epub 2010 May 15.

DOI:10.1016/j.hrthm.2010.05.021
PMID:20580680
Abstract

BACKGROUND

Studies on incidences of sports-related sudden cardiac death (SrSCD) are few and data are needed for the discussion of preparticipation screening for cardiac disease.

OBJECTIVE

We sought to chart the incidence and etiology of SrSCD in the young in Denmark (population 5.4 million) and to compare this to the incidence of sudden cardiac death (SCD) in the background population.

METHODS

All 5,662 death certificates for decedents in the period 2000 to 2006 in the age group 12 to 35 years in Denmark were read independently by 2 physicians to identify cases of SCD. Information from autopsy reports, selected hospital records, and multiple registries was used to identify cases of SCD and SrSCD. SrSCD was defined as SCD occurring during or within 1 hour after exercise in a competitive athlete. The size of the athlete population was estimated from national survey data.

RESULTS

Fifteen (range 0 to 5 per year) cases of SrSCD were found, 8 of which had antecedent symptoms. The incidence rate was 1.21 (95% confidence interval [CI]: 0.68 to 2.00) per 100,000 athlete person-years. The most common autopsy findings were arrhythmogenic right ventricular cardiomyopathy (n = 4), sudden unexplained death (n = 4), and coronary artery disease (n = 2). The incidence of SCD in the general population age 12 to 35 was 3.76 (95% CI: 3.42 to 4.14) per 100,000 person-years.

CONCLUSION

In Denmark, SrSCD is a rare occurrence and the incidence rate is lower than that of SCD in the general population. This may imply a low value of preparticipation screening of athletes in Denmark.

摘要

背景

关于运动相关心源性猝死(SrSCD)发生率的研究较少,需要数据来讨论心脏病的参赛前筛查。

目的

我们旨在绘制丹麦年轻人中 SrSCD 的发生率和病因,并将其与背景人群中心律失常性心源性猝死(SCD)的发生率进行比较。

方法

对丹麦 2000 年至 2006 年期间年龄在 12 至 35 岁之间的所有 5662 份死亡证明进行了独立阅读,由 2 名医生识别 SCD 病例。从尸检报告、选定的医院记录和多个登记处获取信息,以识别 SCD 和 SrSCD 病例。SrSCD 定义为在竞技运动员运动中或运动后 1 小时内发生的 SCD。运动员人群的规模是根据全国调查数据估计的。

结果

发现 15 例(每年 0 至 5 例)SrSCD,其中 8 例有前驱症状。发生率为每 10 万名运动员 1.21(95%置信区间:0.68 至 2.00)。最常见的尸检发现为致心律失常性右心室心肌病(n=4)、突发性不明原因死亡(n=4)和冠状动脉疾病(n=2)。年龄在 12 至 35 岁的普通人群中 SCD 的发生率为每 100,000 人年 3.76(95%置信区间:3.42 至 4.14)。

结论

在丹麦,SrSCD 是一种罕见的情况,发生率低于普通人群中的 SCD。这可能意味着丹麦运动员参赛前筛查的价值较低。

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