UCT/MRC Research Unit for Exercise Science and Sports Medicine, Department of Human Biology, Faculty of Health Sciences, University of Cape Town, South Africa.
Br J Sports Med. 2011 Nov;45(14):1113-8. doi: 10.1136/bjsm.2010.071951. Epub 2010 Jun 28.
To investigate which of two commonly used treatment protocols for exercise-associated postural hypotension (EAPH) resulted in earlier discharge from the medical facility.
This randomised clinical field trial was undertaken at two Ironman Triathlon competitions and one ultra-distance footrace. All collapsed athletes admitted to the medical facilities were considered for the trial. Following clinical assessment and special investigations to confirm the diagnosis of EAPH, 28 athletes were randomly assigned to an oral fluid and Trendelenburg position (OT=14) or an intravenous fluid (IV=14) treatment group. Following admission fluid intake was recorded, and all athletes were assessed clinically (blood pressure, heart rate, level of consciousness) every 15 min until discharge criteria were met. The main measure of outcome was the time to discharge (min).
On admission, subjects in the OT and IV groups were similar with respect to age, systolic blood pressure, heart rate and serum sodium concentration. There were no significant differences in heart rate, systolic and diastolic blood pressure between groups and over time until discharge. The fluid intake during the treatment period was significantly greater in the IV group (IV 1045 ± 185 ml, OT 204 ± 149 ml; p<0.001). The average time to discharge for the OT group (58 ± 23 min) was similar to that of the IV group (52.5 ± 18 min; p=0.47).
Endurance athletes with EAPH can be treated effectively using the Trendelenburg position and oral fluids and the administration of intravenous fluids does not reduce the time to discharge. The findings of this study support the hypothesis that EAPH is a result of venous pooling due to peripheral vasodilatation, rather than dehydration.
探究两种常用于治疗运动相关体位性低血压(EAPH)的治疗方案中,哪一种能使患者更早地从医疗机构出院。
本随机临床现场试验在两项铁人三项比赛和一项超长距离赛跑中进行。所有因晕倒而被送入医疗机构的运动员都符合试验条件。在进行临床评估和特殊检查以确认 EAPH 诊断后,将 28 名运动员随机分配到口服补液和仰卧位(OT=14)或静脉补液(IV=14)治疗组。入院后记录液体摄入量,所有运动员每 15 分钟接受一次临床评估(血压、心率、意识水平),直到符合出院标准。主要的结局测量指标是出院时间(分钟)。
入院时,OT 和 IV 组的受试者在年龄、收缩压、心率和血清钠浓度方面相似。在心率、收缩压和舒张压方面,两组之间以及在出院前的时间内均无显著差异。治疗期间 IV 组的液体摄入量明显高于 OT 组(IV 组 1045±185ml,OT 组 204±149ml;p<0.001)。OT 组的平均出院时间(58±23 分钟)与 IV 组相似(52.5±18 分钟;p=0.47)。
EAPH 的耐力运动员可以通过使用仰卧位和口服补液来有效治疗,而静脉补液并不能缩短出院时间。本研究的结果支持 EAPH 是由于外周血管扩张导致静脉充血而不是脱水引起的假设。