Mishin Igor, Ghidirim Gheorghe, Vozian Marin
First Department of Surgery N. Anestiadi & Laboratory of Hepato-Pancreato-Biliary Surgery, Medical University N. Testemitsanu, National Center of Emergency Medicine, Kishinev, Moldova.
J Gastrointest Cancer. 2012 Jun;43(2):349-53. doi: 10.1007/s12029-010-9181-9.
Mucinous cystadenocarcinoma of the appendix with invasion of the anterior abdominal wall and cutaneous fistula development is a rare condition. To the best of the authors' knowledge, five such cases have been reported in the medical literature.
The patient was a 68-year-old man who presented with a mass growing through the incisional scar and a skin fistula with mucinous discharge 1 year after appendectomy via McBurney's incision. Carcinoembroyonic antigen and carbohydrate antigen 19-9 concentration was elevated. Abdominal computed tomography scan revealed a mass in the cecum with involvement of the abdominal wall. Right hemicolectomy with en bloc abdominal wall implant and skin fistula resection with clear margins was performed.
The patient received intraperitoneal intra- and postoperative chemotherapy. Gross examination of the specimen showed a mass emerging from the remnant stump of the appendix. The patient showed no relapse 1 year after surgery. Clinical, paraclinical features, and treatment options are discussed with review of the literature.
阑尾黏液性囊腺癌侵犯前腹壁并形成皮肤瘘是一种罕见情况。据作者所知,医学文献中已报道了5例此类病例。
患者为一名68岁男性,在经麦氏切口行阑尾切除术后1年,出现经切口瘢痕生长的肿块及有黏液样分泌物的皮肤瘘。癌胚抗原和糖类抗原19-9浓度升高。腹部计算机断层扫描显示盲肠有一肿块,累及腹壁。行右半结肠切除术并整块切除腹壁植入物及皮肤瘘,切缘清晰。
患者接受了术中及术后腹腔内化疗。标本大体检查显示肿块起源于阑尾残端。患者术后1年无复发。结合文献复习讨论了临床、副临床特征及治疗选择。