Nagata Hiroshi, Kondo Yuji, Kawai Kazushige, Ishihara Soichiro, Kazama Shinsuke, Nirei Takako, Soma Daisuke, Yamada Jun, Sunami Eiji, Kitayama Joji, Kubota Yoshiro, Watanabe Toshiaki
Division of Surgical Oncology, Department of Surgery, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Department of Surgery, Kikkoman General Hospital, 100 Miyazaki, Noda-city, Chiba, 278-0005, Japan.
World J Surg Oncol. 2016 Mar 5;14:64. doi: 10.1186/s12957-016-0828-2.
Mucinous cystadenocarcinoma is the second most common etiology of appendiceal mucocele. We report a relatively rare case of a giant appendiceal mucocele caused by mucinous cystadenocarcinoma, which occupied the entire abdomen of an adult woman.
A 63-year-old woman presented with a chief complaint of abdominal distention. Imaging studies showed a giant cystic mass occupying her entire abdomen. Laparotomy confirmed a giant appendiceal mucocele, and the patient underwent ileocecal resection. A mucinous deposit was not found in her abdominal cavity, and the ovaries were grossly normal bilaterally. The pathological diagnosis was mucinous adenocarcinoma with a low-grade mucinous neoplasm that invaded the subserosa. Regional lymph node metastasis was not found. She has had recurrence-free survival for 5 years.
The present case is the largest appendiceal cystadenocarcinoma ever reported. The optimal treatment of an appendiceal neoplasm requires further research based on consensus terminology of an appendiceal mucocele.
黏液性囊腺癌是阑尾黏液囊肿的第二常见病因。我们报告了一例相对罕见的由黏液性囊腺癌引起的巨大阑尾黏液囊肿病例,该囊肿占据了一名成年女性的整个腹部。
一名63岁女性以腹胀为主诉就诊。影像学检查显示一个巨大的囊性肿块占据了她的整个腹部。剖腹手术证实为巨大阑尾黏液囊肿,患者接受了回盲部切除术。在她的腹腔中未发现黏液沉积物,双侧卵巢大体正常。病理诊断为黏液腺癌伴低度黏液性肿瘤,侵犯浆膜下层。未发现区域淋巴结转移。她已无复发生存5年。
本病例是有报道以来最大的阑尾囊腺癌。阑尾肿瘤的最佳治疗方法需要基于阑尾黏液囊肿的共识术语进行进一步研究。