de Oliveira Magda Lúcia Félix, Buriola Aline Aparecida
Universidade Estadual de Maringá (UEM), Maringá, Paraná, Brasil.
Rev Gaucha Enferm. 2009 Dec;30(4):648-55. doi: 10.1590/s1983-14472009000400010.
This article has as objective the discussion of the severity of intoxications by cholinesterase inhibitor insecticides, which happened in the Northwest of Paraná, Brazil, starting from an exploratory descriptive study with retrospective analysis of epidemiological data sheets of the Intoxications Control Center in the University Hospital of Maringá, Paraná, Brazil, referring to patients intoxicated from January, 1994 to December 2005. 529 cases were analyzed, 168 (31,7%) for organophosphates and 167 (31,5%) for carbamate. The suicide attempt represented 257 cases (48,5%), the occupational exposure 140 (26,5%), and the accidental 124 (23,5%). Comparing the number of severe intoxications and deaths, it was verified from 100% of deaths to cases severe occupational exposure, 20% for the suicide attempt and 7,5% deaths for the accidental intoxications classified as severe. The high incidence of serious intoxication and mortality suggest preventive strategies in respect of the usage of the insecticides, aiming to restrict the indiscriminate access to these powerful toxic agents.
本文旨在探讨巴西巴拉那州西北部发生的胆碱酯酶抑制剂杀虫剂中毒的严重程度，该研究始于一项探索性描述性研究，对巴西巴拉那州马林加大学医院中毒控制中心1994年1月至2005年12月期间中毒患者的流行病学数据表进行回顾性分析。共分析了529例病例，其中168例（31.7%）为有机磷中毒，167例（31.5%）为氨基甲酸酯中毒。自杀未遂占257例（48.5%），职业暴露占140例（26.5%），意外中毒占124例（23.5%）。比较重度中毒和死亡人数发现，职业暴露重度中毒病例的死亡率为100%，自杀未遂者的死亡率为20%，归类为重度的意外中毒的死亡率为7.5%。严重中毒和死亡率高表明在杀虫剂使用方面应采取预防策略，旨在限制对这些强效有毒制剂的随意获取。
