Policy Analysis Inc, Four Davis Ct, Brookline, MA 02445, USA.
Am J Manag Care. 2010 May;16(5 Suppl):S126-37.
To compare healthcare utilization and costs in the year preceding and following initial diagnosis of fibromyalgia (FM).
Using a large US health insurance claims database, we identified all persons with newly diagnosed FM (International Classification of Diseases, Ninth Revision, Clinical Modification diagnosis code 729.1) between January 1, 2003, and December 31, 2005 ("FM patients"). Each patient's first-noted claim with a diagnosis of FM was designated the "index date," and all pharmacy, outpatient, and inpatient claims were compiled over the 12-month periods preceding and following this date ("prediagnosis" and "postdiagnosis," respectively). Patients with incomplete pre- or postdiagnosis data were excluded. Healthcare utilization and costs were compared between the 2 periods.
A total of 1803 patients met all study inclusion criteria; mean (SD) age was 50.4 (9.4) years; 91% were women. Comorbidities were common, including arthritis (21% of study subjects), back pain (20%), and painful neuropathic disorders (16%). The percentage of study subjects receiving various pain-related medications increased from pre- to postdiagnosis, including opioids (51.3% vs 55.9%), antiepileptics (22.6% vs 28.6%), and tricyclic antidepressants (15.5% vs 21.2%) (all P <.01). Mean total healthcare costs also increased by $1725 between these periods (mean [95% confidence interval]: $9324 [$8655, $10,092] vs $11,049 [$10,245, $11,973], respectively; P <.01).
Patients with FM are often seen for other medical problems prior to initial diagnosis. Levels of healthcare utilization and costs are high during both the pre- and postdiagnosis periods.
比较纤维肌痛(fibromyalgia,FM)初始诊断前后一年的医疗保健利用和费用。
使用美国大型医疗保险索赔数据库,我们确定了 2003 年 1 月 1 日至 2005 年 12 月 31 日期间新诊断为 FM(国际疾病分类,第九修订版,临床修正诊断代码 729.1)的所有人(FM 患者)。每位患者首次记录的 FM 诊断索赔被指定为“索引日期”,并在该日期之前和之后的 12 个月内编制所有药房、门诊和住院索赔(分别为“诊断前”和“诊断后”)。排除了在预诊断或诊断后数据不完整的患者。比较了这两个时期的医疗保健利用和费用。
共有 1803 名患者符合所有研究纳入标准;平均(SD)年龄为 50.4(9.4)岁;91%为女性。合并症很常见,包括关节炎(21%的研究对象)、背痛(20%)和疼痛性神经病变(16%)。从诊断前到诊断后,接受各种与疼痛相关药物治疗的研究对象比例增加,包括阿片类药物(51.3%对 55.9%)、抗癫痫药(22.6%对 28.6%)和三环类抗抑郁药(15.5%对 21.2%)(均 P <.01)。这两个时期的总医疗保健费用平均增加了 1725 美元(平均值[95%置信区间]:9324 美元[8655 美元,10092 美元]与 11049 美元[10245 美元,11973 美元];均 P <.01)。
在初始诊断之前,纤维肌痛患者通常会因其他医疗问题就诊。在诊断前和诊断后期间,医疗保健的利用水平和费用都很高。