Seddon Mike, Curzen Nick
Wessex Cardiac Unit, Southampton University Hospitals NHS Trust, Tremona Road, Southampton SO16 6YD, UK.
J Ren Care. 2010 May;36 Suppl 1:118-26. doi: 10.1111/j.1755-6686.2010.00157.x.
Chronic kidney disease (CKD) is associated with a high burden of coronary artery disease, myocardial infarction and cardiovascular death. Management of patients with CKD presenting with acute coronary syndromes is more complex than in the general population, due to greater diagnostic uncertainty and the lack of direct evidence for therapeutic interventions in this specific population, coupled with concerns about therapy-related adverse effects. However, these patients potentially have much to gain from conventional revascularisation strategies used in the general population. This review summarises the current evidence regarding the treatment of patients with CKD presenting with acute coronary syndromes, in particular with respect to coronary revascularisation strategies.
慢性肾脏病（CKD）与冠状动脉疾病、心肌梗死及心血管死亡的高负担相关。因诊断不确定性更高、缺乏针对这一特定人群治疗干预的直接证据，以及对治疗相关不良反应的担忧，CKD合并急性冠脉综合征患者的管理比普通人群更为复杂。然而，这些患者可能从普通人群中使用的传统血运重建策略中获益良多。本综述总结了目前关于CKD合并急性冠脉综合征患者治疗的证据，特别是在冠状动脉血运重建策略方面。
