Institute of Nephrology, Peking University First Hospital, Beijing, China.
Nephrology (Carlton). 2010 Jun;15 Suppl 2:18-22. doi: 10.1111/j.1440-1797.2010.01306.x.
Low birthweight reflects the congenital defects of organs, which is associated with chronic kidney disease through its direct influence on nephron number and function, also through related metabolic disease-induced kidney damage. We reviewed the current evidence regarding the role of low birthweight in the pathogenesis of chronic kidney disease.
低出生体重反映了器官的先天性缺陷,它通过直接影响肾单位数量和功能,以及通过相关代谢性疾病引起的肾损伤,与慢性肾脏病相关。我们综述了目前关于低出生体重在慢性肾脏病发病机制中的作用的证据。