Public Health Department, Montreal Health and Social Services Agency, Montreal, Quebec, Canada.
Diabetes Care. 2010 Jul;33(7):1491-3. doi: 10.2337/dc09-2215.
To confirm the existence of an increased risk of complications from influenza A (H1N1)p among patients with diabetes.
Using data from an enhanced influenza surveillance project in Montreal, Canada, and age/sex-specific population estimates of diabetes prevalence, we estimated the risk of hospitalization among persons with diabetes. Comparing hospitalized patients admitted or not to an intensive care unit (ICU), we estimated the risk of ICU admission associated with diabetes, controlling for other patient characteristics.
Among 239 hospitalized patients with PCR-confirmed influenza A (H1N1)p, 162 (68%) were interviewed, of whom 22 had diabetes, when 7.1 were expected (prevalence ratio 3.10 [95% CI 2.04-4.71]). The odds ratio for ICU admission was 4.29 (95% CI 1.29-14.3) among hospitalized patients with diabetes compared to those without.
Diabetes triples the risk of hospitalization after influenza A (H1N1)p and quadruples the risk of ICU admission once hospitalized.
确认糖尿病患者感染甲型 H1N1 流感后的并发症风险增加。
利用加拿大蒙特利尔加强型流感监测项目的数据和特定年龄/性别糖尿病流行率的人口估计数，我们评估了糖尿病患者的住院风险。通过比较住院患者是否入住重症监护病房（ICU），我们评估了糖尿病与 ICU 入院相关的风险，同时控制了其他患者特征。
在 239 例经聚合酶链反应（PCR）确诊的甲型 H1N1p 流感住院患者中，对 162 例（68%）进行了访谈，其中 22 例患有糖尿病，而预期有 7.1 例（患病率比为 3.10 [95% CI 2.04-4.71]）。与无糖尿病的住院患者相比，糖尿病患者 ICU 入院的比值比为 4.29（95% CI 1.29-14.3）。
糖尿病使甲型 H1N1p 流感后住院的风险增加两倍，使住院后 ICU 入院的风险增加三倍。
