Psychiatry Consultation Service, 260 Stetson St., Suite 3200; P.O. Box 0559, Cincinnati, OH 45267-0559, USA.
Psychosomatics. 2010 Jul-Aug;51(4):356-356.e3. doi: 10.1176/appi.psy.51.4.356.
Rhabdomyolysis involves the release of intracellular contents secondary to muscle cell injury; it generally presents with muscle pain and weakness. Illicit drugs, including phencyclidine, MDMA ("ecstasy"), and cocaine, are frequently documented as a cause of rhabdomyolysis.
The authors review the literature on LSD-associated rhabdomyolysis.
The authors provide a new case report of a previously health patient who suffered rhabdomyolysis after LSD ingestion.
Although frequently listed as a cause of rhabdomyolysis, there are only limited reports of rhabdomyolysis in patients who have ingested LSD.
The discussion outlines potential mechanisms and management of LSD-associated rhabdomyolysis. Consultation psychiatrists may be called to assist in management of acute mental-status changes or agitation associated with LSD intoxication in addition to facilitating subsequent chemical-dependency treatment.
横纹肌溶解症是由于肌肉细胞损伤导致细胞内物质释放引起的，通常表现为肌肉疼痛和无力。苯环已哌啶（PCP）、摇头丸（MDMA）和可卡因等非法药物经常被记录为横纹肌溶解症的原因。
作者回顾了与 LSD 相关的横纹肌溶解症的文献。
作者提供了一个新的案例报告，一名以前健康的患者在服用 LSD 后出现横纹肌溶解症。
尽管 LSD 经常被列为横纹肌溶解症的原因之一，但只有有限的报告显示 LSD 摄入患者出现横纹肌溶解症。
讨论概述了 LSD 相关横纹肌溶解症的潜在机制和管理。除了促进随后的化学依赖治疗外，还可能需要咨询精神科医生来协助管理 LSD 中毒引起的急性精神状态改变或激越。
