Pediatric Department, Hospital A. C. Camargo, Rua Prof. Antônio Prudente, Sao Paulo, SP, Brazil.
Pediatr Blood Cancer. 2010 Dec 1;55(6):1167-71. doi: 10.1002/pbc.22644.
The loss of a child is considered the hardest moment in a parent's life. Studies addressing length of survival under pediatric palliative care are rare. The aim of this study was to improve a survival prediction model for children in palliative care, as accurate information positively impacts parent and child preparation for palliative care.
Sixty-five children referred to a pediatric palliative care team were followed from August 2003 until December 2006. Variables investigated (also included in previous studies) were: diagnosis, home care provider, presence of anemia, and performance status score given by the home care provider. Clinical variables such as symptom number were also used to test the score's ability to predict survival.
The length of survival prognostic score was validated using the above variables. The number of symptoms at transition to palliative care does not improve the score's predictive ability. The sum of the single scores gives an overall score for each patient, dividing the population into three groups by probability of 60-day survival: Group A 80.0%, Group B 38.0%, and Group C 28.5% (P < 0.001).
A pediatric palliative care score based on easily accessible variables is statistically significant in multivariate analysis. Factors that increase accuracy of life expectancy prediction enable adequate information to be given to patients and families, contributing to therapeutic decision-making issues.
失去孩子被认为是父母一生中最艰难的时刻。针对儿科姑息治疗下的生存时间的研究很少。本研究旨在改进儿科姑息治疗儿童的生存预测模型,因为准确的信息可以积极影响姑息治疗的父母和儿童的准备。
从 2003 年 8 月到 2006 年 12 月,对 65 名转介至儿科姑息治疗小组的儿童进行了随访。调查的变量(也包含在以前的研究中)包括:诊断、家庭护理提供者、是否存在贫血以及家庭护理提供者给出的表现状态评分。还使用临床变量,如症状数量,来测试评分预测生存能力。
使用上述变量验证了生存预后评分。在过渡到姑息治疗时症状的数量并不能提高评分的预测能力。各单项评分的总和为每个患者提供了一个总体评分,根据 60 天生存率的概率将人群分为三组:A 组 80.0%、B 组 38.0%和 C 组 28.5%(P<0.001)。
基于易于获取的变量的儿科姑息治疗评分在多变量分析中具有统计学意义。增加预期寿命预测准确性的因素能够为患者和家庭提供充分的信息,有助于治疗决策问题。