Webb W R
Radiology. 1978 May;127(2):309-13. doi: 10.1148/127.2.309.
The pleural tail sign is widely thought to indicate malignancy. However, of 18 patients with the tail sign, 9 had benign disease. Bronchioloalveolar carcinoma was the most common malignant tumor, but adenocarcinoma, squamous-cell carcinoma, and metastatic adenocarcinoma of the colon were also found. The location of nodules and the radiographic characteristics of the pleural tails did not help differentiate benign from malignant lesions. However, nodules 2 cm or larger were malignant while those 1 cm or smaller were benign. Histologically, pleural tails reflected thickened, fibrotic connective tissue septae with indrawing of the visceral pleura. Their occurrence with neoplasm reflects desmoplastic reaction or scar carcinoma.
胸膜尾征被广泛认为提示恶性病变。然而，在18例有胸膜尾征的患者中，9例患有良性疾病。细支气管肺泡癌是最常见的恶性肿瘤，但也发现了腺癌、鳞状细胞癌和结肠转移性腺癌。结节的位置及胸膜尾征的影像学特征无助于鉴别良性与恶性病变。然而，直径2cm或更大的结节为恶性，而直径1cm或更小的结节为良性。组织学上，胸膜尾征反映为增厚的、纤维化的结缔组织间隔伴脏层胸膜内陷。它们与肿瘤同时出现反映了促结缔组织增生性反应或瘢痕癌。
