Matsune S, Sando I, Takahashi H
Department of Otolaryngology, University of Pittsburgh School of Medicine, Eye and Ear Institute of Pittsburgh, Pennsylvania 15213.
Ann Otol Rhinol Laryngol. 1991 Jun;100(6):439-46. doi: 10.1177/000348949110000602.
Differences in insertion of the tensor veli palatini muscle (TVPM) into the lateral lamina of the eustachian tube (ET) cartilage between cleft palate (CP) cases and controls were investigated histologically. Thirty temporal bones with entire ETs were studied: 10 from individuals with CP and 20 controls. The ratio of the length of the ET cartilage with insertion of the TVPM to its total length from the nasopharyngeal end to near the tubal isthmus was calculated in all 30 cases. In all 20 controls, but in only 6 of 10 CP cases, the TVPM inserted into the lateral lamina of the ET cartilage at its tip portion (chi 2 test, p less than .025). The ratio was significantly smaller in CP cases (0.178 +/- 0.172) than in controls (0.419 +/- 0.120) (t = 4.305, p less than .001). We believe that abnormal insertion of the TVPM into the ET cartilage is one of the causes of the functional obstruction of the ET that contributes to the frequent bouts of otitis media experienced by those with cleft palate.
通过组织学方法研究腭裂(CP)病例与对照组之间腭帆张肌(TVPM)插入咽鼓管(ET)软骨外侧板的差异。研究了30块带有完整ET的颞骨:10块来自CP个体,20块为对照。计算了所有30例中TVPM插入处的ET软骨长度与其从鼻咽端到咽鼓管峡部附近总长度的比值。在所有20例对照中,TVPM均插入ET软骨外侧板的顶端部分,但10例CP病例中只有6例如此(卡方检验,p<0.025)。CP病例的比值(0.178±0.172)显著低于对照组(0.419±0.120)(t=4.305,p<0.001)。我们认为,TVPM异常插入ET软骨是导致ET功能障碍的原因之一,这也是腭裂患者频繁患中耳炎的原因。