Sarnat B G
Research Institute, Cedars-Sinai Medical Center, Los Angeles, California.
Ann Otol Rhinol Laryngol. 1991 Jun;100(6):508-15. doi: 10.1177/000348949110000615.
The purpose of this report is to review and summarize a selected series of previously reported experiments at the nasoseptovomeral region dealing with both normal growth and the effects of certain operative procedures in young and adult rabbits. The methods of study included gross and serial cephalometric radiography with radiopaque implants, histology, and autoradiography. Findings indicated that the frontonasal suture region was an active secondary site of growth unaffected by extirpation. Examples of differential sutural growth were presented. The proximal and distal regions of both the nasal bone and septum were their most active sites of growth. Extirpations of the central section of the cartilaginous nasal septum resulted in severe upper facial deformity in young but not in adult rabbits. Trauma to the nasal bone region in the young rabbit did not result in severe facial deformity as did trauma to the cartilaginous nasal septum. Another purpose of this report is to present some of the different approaches used to study the nasoseptovomeral region.
本报告的目的是回顾和总结一系列先前报道的、针对幼兔和成年兔鼻隔犁骨区域的实验,这些实验涉及正常生长以及某些手术操作的影响。研究方法包括使用不透射线植入物的大体和系列头颅测量放射摄影、组织学和放射自显影。研究结果表明,额鼻缝区域是一个活跃的继发性生长部位,不受切除的影响。文中给出了不同缝线生长的例子。鼻骨和鼻中隔的近端和远端区域是它们最活跃的生长部位。切除软骨性鼻中隔的中央部分会导致幼兔严重的上面部畸形,但成年兔不会。幼兔鼻骨区域的创伤不会像软骨性鼻中隔创伤那样导致严重的面部畸形。本报告的另一个目的是介绍一些用于研究鼻隔犁骨区域的不同方法。