Parkinson disease and Movement Disorders Unit, Neurology Service, Faculty of Medicine, Institut Clínic de Neurociències, Centro de Investigación en Red de Enfermedades Neurodegenerativas, Hospital Clínic, University of Barcelona, Barcelona, Catalonia, Spain.
Eur J Neurol. 2010 Jul;17 Suppl 1:22-7. doi: 10.1111/j.1468-1331.2010.03046.x.
Limb dystonia (LD) refers to dystonia affecting one arm or leg. Depending on the site of onset, age at onset, and the etiology, progression and prognosis will be different. Usually young-onset primary dystonia affects the lower limbs and tends to generalize, while in adult-onset, it appears in the arm and remains focal. Lower limb dystonia in adults is rare as a primary cause, and parkinsonism or other neurological diseases must always be ruled out. In the text that follows, we review the main clinical features of the primary and secondary limb dystonias considering the age at onset and etiology.
肢体肌张力障碍(LD)是指影响单侧手臂或腿部的肌张力障碍。根据发病部位、发病年龄、病因、进展和预后都会有所不同。通常,早发型原发性肌张力障碍影响下肢,且往往呈全身性;而成人发病者,表现为上肢,且仍为局限性。成人原发性下肢肌张力障碍少见,必须始终排除帕金森病或其他神经疾病。下文根据发病年龄和病因,对原发性和继发性肢体肌张力障碍的主要临床特征进行综述。