Department of Obstetrics and Perinatology, Medical University of Lublin, ul. Jaczewskiego 8, 20-950 Lublin, Poland.
J Reprod Immunol. 2010 Nov;86(2):122-5. doi: 10.1016/j.jri.2010.05.004. Epub 2010 Jun 29.
This study investigated the serum concentration of soluble CD30 (sCD30) in pregnant women with isolated fetal intrauterine growth restriction, in pregnancies complicated by preeclampsia with and without accompanying intrauterine growth restriction, and in normotensive healthy pregnant controls. Lower serum concentrations of sCD30 were observed in the group of normotensive pregnant women with a growth-restricted fetus in comparison with the group of healthy pregnant controls, and also in comparison with both preeclamptic groups of pregnant women with and without fetal growth restriction. The concentration of sCD30 in maternal serum from preeclamptic women did not differ in comparison with values from healthy controls or pregnancies complicated by isolated fetal intrauterine growth restriction.
本研究调查了孤立性胎儿宫内生长受限孕妇、伴有或不伴有胎儿宫内生长受限的子痫前期孕妇以及正常血压健康孕妇对照者的血清可溶性 CD30（sCD30）浓度。与健康孕妇对照组相比，正常血压胎儿生长受限孕妇组的血清 sCD30 浓度较低，与伴有和不伴有胎儿生长受限的子痫前期孕妇组相比也是如此。与健康对照组或单纯胎儿宫内生长受限孕妇相比，子痫前期孕妇的血清 sCD30 浓度无差异。
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