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病态肥胖患者全膝关节置换术后的失血情况:计算机导航的影响

Blood loss following total knee replacement in the morbidly obese: Effects of computer navigation.

作者信息

Millar Neal L, Deakin Angela H, Millar Lauren L, Kinnimonth Andrew W G, Picard Frederic

机构信息

Golden Jubilee National Hospital, Department of Orthopaedics, Clydebank, Glasgow, Scotland, UK.

出版信息

Knee. 2011 Mar;18(2):108-12. doi: 10.1016/j.knee.2010.03.002. Epub 2010 Jun 29.

Abstract

Computer navigated total knee arthroplasty (TKA) has several proposed benefits including reduced post-operative blood loss. We compared the total blood volume loss in a cohort of morbidly obese (BMI>40) patients undergoing computer navigated (n=30) or standard intramedullary techniques (n=30) with a cohort of matched patients with a BMI<30 also undergoing navigated (n=31) or standard TKA (n=31). Total body blood loss was calculated from body weight, height and haemotocrit change, using a model which accurately assesses true blood loss as was maximum allowable blood loss which represents the volume of blood that can be lost until a transfusion trigger is required. The groups were matched for age, gender, diagnosis and operative technique. The mean true blood volume loss across all BMI's was significantly (p<0.001) less in the computer assisted group (1014±312ml) compared to the conventional group (1287±330ml). Patients with a BMI>40 and a computer navigated procedure (1105±321ml) had a significantly lower (p<0.001) blood volume loss compared to those who underwent a conventional TKA (1399±330ml). There was no significant difference in the transfusion rate or those reaching the maximum allowable blood loss between groups. This study confirms a significant reduction in total body blood loss between computer assisted and conventional TKA in morbidly obese patients. However computer navigation did not affect the transfusion rate or those reaching the transfusion trigger in the morbidly obese group. Therefore computer navigation may reduce blood loss in the morbidly obese patient but this may not be clinically relevant to transfusion requirements as previously suggested.

摘要

计算机导航全膝关节置换术(TKA)具有多项潜在益处,包括减少术后失血。我们比较了一组病态肥胖(BMI>40)患者接受计算机导航(n = 30)或标准髓内技术(n = 30)时的总失血量,同时与另一组BMI<30且接受导航(n = 31)或标准TKA(n = 31)的匹配患者进行对比。通过体重、身高和血细胞比容变化计算全身失血量,使用的模型能够准确评估实际失血量以及最大允许失血量,最大允许失血量代表在需要输血触发前可丢失的血量。这些组在年龄、性别、诊断和手术技术方面进行了匹配。与传统组(1287±330ml)相比,计算机辅助组(1014±312ml)在所有BMI水平下的平均实际失血量显著更低(p<0.001)。BMI>40且接受计算机导航手术的患者(1105±321ml)与接受传统TKA的患者(1399±330ml)相比,失血量显著更低(p<0.001)。各组之间的输血率或达到最大允许失血量的情况没有显著差异。这项研究证实,在病态肥胖患者中,计算机辅助TKA与传统TKA相比,全身失血量显著减少。然而,计算机导航并未影响病态肥胖组的输血率或达到输血触发标准的情况。因此,计算机导航可能会减少病态肥胖患者的失血量,但这可能与先前认为的输血需求在临床上并无关联。

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