The correlation between poverty and the neglected tropical disease (NTD) burden is undeniable. NTDs are a brand without copyright; an international movement gathering momentum towards a common goal of tackling major causes of preventable illness in low-income countries. New reports by Liese and Schubert and Moran et. al. act as a call to arms, highlighting a need for research into NTD treatment and control that is essential to improving the lives of the 'bottom billion.'