International Center of Excellence in Research in Mali, University of Sciences, Techniques, and Technologies of Bamako, Bamako, Mali
Interdisciplinary School of Health Sciences, University of Ottawa, Ottawa, Ontario, Canada.
BMJ Glob Health. 2024 Oct 9;9(10):e015671. doi: 10.1136/bmjgh-2024-015671.
Five of the neglected tropical diseases use a strategy of preventative chemotherapy distributed via mass drug administration (MDA) for all eligible people living in endemic areas. To be successful, high coverage must be sustained over multiple rounds. Therefore, it will be difficult to reach elimination as a public health problem using MDA if there remain clusters of people who have never been treated. The study aims to explore the reasons why people with high mobility report being never treated during MDA and to provide evidence to support the development of standardised questions for data collection using qualitative research tools.
We conducted an exploratory study using qualitative methods among displaced people, nomads/transhumants and economic migrants who self-reported that they had never been treated during MDA in the health districts of Tominian and Kalabancoro in Mali. Data were collected through in-depth individual interviews and focus group discussions. Nvivo V.14 software was used for data management and analysis.
The main reasons reported for never treatment included: geographical mobility, lack of awareness/information, negative rumours, fear of side effects, conflict and insecurity and logistical difficulties faced in reaching these populations. Proposed solutions included involving communities in the MDA, increasing awareness and information campaigns, effectively managing side effects, and designing and implementing flexible and effective interventions.
This study highlights that there are people with high mobility who may never have been treated during any round of MDA. The reasons for never treatment highlight the challenges faced when reaching particular groups during MDA activities/interventions. Suggested remedies will require programmes to implement more flexible and tailored interventions. Customised approaches based on the context are essential to guarantee fair access to preventive chemotherapy. Effective interventions must consider the supply and demand side in crafting interventions. This research adds to the evidence base to understand never treatment, particularly among highly mobile population groups and in schistosomiasis elimination programmes.
五种被忽视的热带病采用预防性化疗策略,通过大规模药物治疗(MDA)为生活在流行地区的所有符合条件的人提供。要取得成功,必须在多个轮次中保持高覆盖率。因此,如果仍然存在从未接受过治疗的人群聚集,那么通过 MDA 达到消除作为公共卫生问题的目标将非常困难。本研究旨在探讨高流动性人群报告在 MDA 期间从未接受治疗的原因,并提供证据支持使用定性研究工具为数据收集制定标准化问题。
我们在马里的托米尼亚和卡拉班科罗地区的卫生区,对自我报告从未在 MDA 中接受治疗的流离失所者、游牧民族/迁徙者和经济移民进行了一项探索性研究,使用定性方法。通过深入的个人访谈和焦点小组讨论收集数据。使用 Nvivo V.14 软件进行数据管理和分析。
报告的从未治疗的主要原因包括:地理流动性、缺乏意识/信息、负面谣言、对副作用的恐惧、冲突和不安全以及难以接触到这些人群的后勤问题。提出的解决方案包括让社区参与 MDA、提高认识和宣传活动、有效管理副作用,以及设计和实施灵活有效的干预措施。
本研究表明,有高度流动性的人群可能从未在任何一轮 MDA 中接受过治疗。从未治疗的原因突出了在 MDA 活动/干预中接触特定人群所面临的挑战。建议的补救措施将需要方案实施更灵活和定制的干预措施。基于背景的定制方法对于确保公平获得预防性化疗至关重要。有效的干预措施必须考虑供求双方,精心设计干预措施。这项研究增加了对从未治疗的证据基础的了解,特别是在高度流动的人群和血吸虫病消除计划中。