Department of Oral Surgery and Hospital Dentistry,School of Dentistry, Indiana University, 1050 Wishard Blvd., Indianapolis, IN 46202, USA.
J Am Dent Assoc. 2010 Jul;141(7):861-6. doi: 10.14219/jada.archive.2010.0284.
Necrotizing fasciitis is a rapidly spreading, soft-tissue infection involving the subcutaneous tissues. Necrotizing fasciitis originating from a dental-related source is rare. Practitioners should be aware that this infection could occur in patients who are immunocompromised and in patients who are healthy. Practitioners must treat this disease aggressively with surgical debridement and intensive medical support.
The authors present a case report of a man with poorly controlled diabetes mellitus in whom a periapical infection progressed into a maxillofacial space abscess and finally cervical necrotizing fasciitis (CNF). A delay in his initial visit to a dentist was evident. The authors observed a successful outcome in the patient after he underwent several wide surgical debridement procedures, hyperbaric oxygen therapy and a protracted, intensive hospital stay lasting 34 days.
Dentists should suspect that a patient has CNF when maxillofacial cellulitis or an abscess does not respond to conventional therapy. Findings of spreading skin erythema, induration, purple discoloration and anesthesia suggest necrotizing fasciitis. Early computed tomography scans may reveal gas within the deep tissues of the neck, fascial plane involvement or both.
CNF has high morbidity and mortality rates if rapid aggressive therapy is not pursued. Spread of this polymicrobial infection can lead to mediastinitis or cranial base involvement. Mortality is directly proportional to the time to intervention.
坏死性筋膜炎是一种迅速扩散的软组织感染,涉及皮下组织。源于牙科相关来源的坏死性筋膜炎很少见。从业者应该意识到,这种感染可能发生在免疫功能低下的患者和健康的患者中。从业者必须通过外科清创术和强化医疗支持积极治疗这种疾病。
作者报告了一例患有未控制的糖尿病的男性病例,其根尖周感染进展为颌面间隙脓肿,最终发展为颈部坏死性筋膜炎(CNF)。明显存在他初次就诊牙医时延误的情况。在患者接受了多次广泛的清创手术、高压氧治疗和持续 34 天的长时间住院治疗后,作者观察到了成功的结果。
当颌面蜂窝织炎或脓肿对常规治疗无反应时,牙医应怀疑患者患有 CNF。皮肤红斑、硬结、紫绀和麻醉扩散的表现提示坏死性筋膜炎。早期 CT 扫描可能显示颈部深部组织中的气体、筋膜平面受累或两者兼有。
如果不进行快速积极的治疗,CNF 的发病率和死亡率很高。这种多微生物感染的扩散可导致纵隔炎或颅底受累。死亡率与干预时间成正比。