Yoshida H, Yasuhara A, Kobayashi Y
Department of Pediatrics, Kansai Medical University, Osaka, Japan.
Pediatr Neurol. 1991 Mar-Apr;7(2):105-10. doi: 10.1016/0887-8994(91)90005-6.
Using the transcranial Doppler technique to investigate the postnatal and developmental changes of cerebral blood flow in newborn infants, we found that the systolic and mean blood flow velocities increased after birth. A rapid increase in blood flow velocities was demonstrated during the first several days. Pulsatility index, which was initially high, gradually fell after birth and remained stable thereafter. The blood flow velocities of small-for-date infants were determined by their gestational ages. The systolic and mean blood flow velocities were influenced more by postnatal age than by gestational age, birth weight, or body weight. The increase in conceptional age was associated with a decrease in the pulsatility index and an increase in the systolic and mean flow velocities. The transcranial Doppler technique is a useful method and will provide more accurate information about the cerebral hemodynamics in neonates than the previously employed continuous wave Doppler technique.
我们采用经颅多普勒技术研究新生儿出生后及发育过程中脑血流的变化，发现出生后收缩期和平均血流速度增加。在出生后的头几天，血流速度迅速上升。搏动指数最初较高，出生后逐渐下降，此后保持稳定。小于胎龄儿的血流速度取决于其胎龄。收缩期和平均血流速度受出生后年龄的影响大于胎龄、出生体重或体重。孕龄的增加与搏动指数的降低以及收缩期和平均血流速度的增加相关。经颅多普勒技术是一种有用的方法，与先前使用的连续波多普勒技术相比，它将为新生儿脑血流动力学提供更准确的信息。
