Levine Nicholas B, Demonte Franco
Department of Neurosurgery, University of Texas M. D. Anderson Cancer Center, Houston, Texas.
Skull Base. 2010 Jan;20(1):19-22. doi: 10.1055/s-0029-1242980.
Outcomes research has become an integral part of most clinical studies today. Extent of resection, increased median survival, and "time to progression" are no longer the only important end points in need of assessment. Identifying the long-term adverse effects of treatment has become increasingly important as patients try to resume previous activities and an independent lifestyle. The measurement of functional states and health-related quality of life issues are at the forefront of medicine and have become necessary measures of functional outcome following the treatment of a variety of medical and surgical disorders. In this article, we review the most recent studies on the functional outcome of patients undergoing neurological surgeries and its impact on quality of life.
如今,结果研究已成为大多数临床研究不可或缺的一部分。手术切除范围、中位生存期延长以及“疾病进展时间”不再是唯一需要评估的重要终点。随着患者试图恢复以往活动并过上独立生活,确定治疗的长期不良影响变得越来越重要。功能状态的测量以及与健康相关的生活质量问题处于医学前沿,并且已成为治疗各种内科和外科疾病后功能结局的必要衡量指标。在本文中,我们回顾了关于接受神经外科手术患者的功能结局及其对生活质量影响的最新研究。