University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Cardiovasc Intervent Radiol. 2011 Feb;34 Suppl 2:S277-81. doi: 10.1007/s00270-010-9931-x. Epub 2010 Jul 1.
Cryotherapy is the application of varying extremes of cold temperatures to destroy abnormal tissue. The intent of this article is to describe a novel technique using percutaneous cryotherapy for treating a noninvoluting congenital craniofacial hemangioma (NICH). An 18-year-old woman with type 1 von Willebrand's disease, as well as a qualitative platelet aggregation disorder, presented with multiple recurrent episodes of oral bleeding from a NICH involving the right buccal space and maxillary tuberosity. The patient was initially treated with a combination of endovascular particulate embolization, percutaneous sclerotherapy, tissue cauterization, and laser therapy between the ages of 4 and 8 years of age. At 18 years of age, the patient presented with recurrent episodes of oral bleeding related to the NICH. Endovascular embolization was performed using particulate and a liquid embolic agent with limited success. Due to the refractory nature of this bleeding, the patient underwent successful lesion ablation using percutaneous cryotherapy. At 9-month follow-up, the patient is asymptomatic with no episodes of recurrent bleeding.
冷冻疗法是将不同极端的低温应用于破坏异常组织。本文的目的是描述一种使用经皮冷冻疗法治疗非消退性先天性颅面血管瘤(NICH)的新方法。一名 18 岁的女性患有 1 型 von Willebrand 病和定性血小板聚集障碍,右侧颊间隙和上颌结节处存在涉及多个复发性口腔出血的 NICH。该患者在 4 至 8 岁期间最初接受了血管内颗粒栓塞、经皮硬化治疗、组织烧灼和激光治疗的联合治疗。18 岁时,患者出现与 NICH 相关的复发性口腔出血。使用颗粒状和液体栓塞剂进行血管内栓塞取得了有限的成功。由于这种出血的难治性,患者接受了经皮冷冻疗法成功的病变消融。在 9 个月的随访中,患者无症状,无复发性出血发作。