• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

骨髓瘤细胞核内包涵体的起源。

Origin of intranuclear inclusions in myeloma cells.

作者信息

Djaldetti M, Lewinski U H

出版信息

Scand J Haematol. 1978 Mar;20(3):200-5. doi: 10.1111/j.1600-0609.1978.tb02448.x.

DOI:10.1111/j.1600-0609.1978.tb02448.x
PMID:205940
Abstract

The mechanism of inclusion of the cytoplasmic dense bodies into the nucleus of myeloma cells was studied by transmission electron microscopy. The findings in different cells suggest that the inclusion of the electron-dense bodies is a result of an interaction between the nuclear envelope and the endoplasmic reticulum. The ability of the nuclear membrane to form an extension into the cytoplasm and the connection with the cisternae of endoplasmic reticulum enables the movement of the dense bodies towards the nucleus. The proposed mechanism does not support the concept of a simple invagination of the bodies into the nucleus or that they are produced in the nucleus itself.

摘要

通过透射电子显微镜研究了骨髓瘤细胞质致密体进入细胞核的机制。不同细胞中的研究结果表明,电子致密体的进入是核膜与内质网相互作用的结果。核膜形成延伸至细胞质并与内质网池连接的能力,使得致密体能够向细胞核移动。所提出的机制不支持致密体简单内陷进入细胞核或它们在细胞核内产生的概念。

相似文献

1
Origin of intranuclear inclusions in myeloma cells.骨髓瘤细胞核内包涵体的起源。
Scand J Haematol. 1978 Mar;20(3):200-5. doi: 10.1111/j.1600-0609.1978.tb02448.x.
2
Bone marrow culture and autoradiography of IgA myeloma plasmocytes with intranuclear inclusion bodies.伴有核内包涵体的IgA骨髓瘤浆细胞的骨髓培养及放射自显影
Scand J Haematol. 1978 Oct;21(4):341-8. doi: 10.1111/j.1600-0609.1978.tb00375.x.
3
Electron microscopic observation of inclusion bodies in plasma cells of multiple myeloma and Waldenström's macroglobulinemia.多发性骨髓瘤和华氏巨球蛋白血症浆细胞中包涵体的电子显微镜观察。
Tohoku J Exp Med. 1975 Nov;117(3):257-81. doi: 10.1620/tjem.117.257.
4
[Nuclear inclusions in plasma cells. Ultrastructural study].
Sangre (Barc). 1986;31(2):180-6.
5
Intranuclear inclusions in myeloma cells in a case of nonsecretory multiple myeloma.
Am J Hematol. 1990 Jan;33(1):72-4. doi: 10.1002/ajh.2830330115.
6
Intranuclear inclusions in Bence Jones kappa myeloma.本-周蛋白κ链骨髓瘤中的核内包涵体
Nihon Ketsueki Gakkai Zasshi. 1981 Feb;44(1):102-7.
7
Helical inclusions with nucleopore-like characteristics in the cytoplasm of Swiss 3T3 cells: a preliminary communication.瑞士3T3细胞胞质中具有核孔样特征的螺旋状包涵体:初步通讯
Cell Biol Int. 1993 Nov;17(11):1033-8. doi: 10.1006/cbir.1993.1033.
8
Heat induced ultrastructural injuries in lymphoid cells.
Exp Mol Pathol. 1978 Dec;29(3):281-90. doi: 10.1016/0014-4800(78)90071-0.
9
Fine structure of the pars intermedia in the rhesus monkey, Macaca mulatta.恒河猴(猕猴)垂体中间部的精细结构
J Anat. 1974 Sep;118(Pt 1):155-69.
10
Ultrastructural study of focal epithelial hyperplasia.局灶性上皮增生的超微结构研究
Oral Surg Oral Med Oral Pathol. 1975 Apr;39(4):622-9. doi: 10.1016/0030-4220(75)90204-2.

引用本文的文献

1
Genesis of concentric laminated inclusions in the nucleus.
Experientia. 1980 Jan 15;36(1):59-61. doi: 10.1007/BF02003971.
2
Intracisternal inclusions in Schwann cells of the sural nerve.
Acta Neuropathol. 1992;83(6):664-6. doi: 10.1007/BF00299418.