Department of Animal Medicine and Surgery, Veterinary School of Córdoba, University of Córdoba, Francisco Santisteban Hospital, Campus de Rabanales 14014, Córdoba, Spain.
Vet J. 2011 Jun;188(3):352-5. doi: 10.1016/j.tvjl.2010.06.001. Epub 2010 Jul 1.
The use of spectral entropy to determine anaesthetic depth and antinociception was evaluated in sevoflurane-anaesthetised Beagle dogs. Dogs were anaesthetised at each of five multiples of their individual minimum alveolar concentrations (MAC; 0.75, 1, 1.25, 1.5 and 1.75 MAC), and response entropy (RE), state entropy (SE), RE-SE difference, burst suppression rate (BSR) and cardiorespiratory parameters were recorded before and after a painful stimulus. RE, SE and RE-SE difference did not change significantly after the stimuli. The correlation between MAC-entropy parameters was weak, but these values increased when 1.75 MAC results were excluded from the analysis. BSR was different to zero at 1.5 and 1.75 MAC. It was concluded that RE and RE-SE differences were not adequate indicators of antinociception and SE and RE were unable to detect deep planes of anaesthesia in dogs, although they both distinguished the awake and unconscious states.
使用光谱熵来确定七氟醚麻醉下比格犬的麻醉深度和镇痛效果。在 5 个比格犬个体最低肺泡浓度（MAC；0.75、1、1.25、1.5 和 1.75 MAC）的倍数下，对犬进行麻醉，并在疼痛刺激前后记录反应熵（RE）、状态熵（SE）、RE-SE 差值、爆发抑制率（BSR）和心肺参数。刺激后，RE、SE 和 RE-SE 差值没有明显变化。MAC-熵参数之间的相关性较弱，但当排除 1.75 MAC 结果进行分析时，这些值增加。BSR 在 1.5 和 1.75 MAC 时与零不同。结论是，RE 和 RE-SE 差异不是镇痛的充分指标，SE 和 RE 无法检测到犬的深麻醉平面，尽管它们都可以区分清醒和无意识状态。
