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[Hepatic activity of glutathione transferase and bromsulphalein metabolism].

作者信息

Serra M A, Caballero A, Aparisi L, Rodrigo J M, Del Olmo J A, Ferrando J, Wassel A H, Reig G, Bixquert M

出版信息

Rev Esp Enferm Dig. 1991 Feb;79(2):112-6.

PMID:2059513
Abstract

The gluthatione transferase activity has been studied in liver biopsies from patients suffering with different hepatic lesion and related to the bromsulphalein (BSP) maximal transport (MT) and the conjugated dye present in serum. Results prove that the MT of BSP is independent of the enzyme activity, but is correlated to the conjugated BSP present in serum during the first perfusion. The enzyme activity, the MT of BSP and BSP conjugated rare in serum are not related to the liver lesion stage. From the analysis of our results we conclude that in the beginning the BSP conjugated proportion is determined by the enzyme activity which is not a restrictive factor of the BSP maximal transport.

摘要

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引用本文的文献

1
Maximal biliary transport of sulfobromophthalein in patients with a T-tube placed in the common bile duct.
Eur J Drug Metab Pharmacokinet. 1997 Apr-Jun;22(2):135-9. doi: 10.1007/BF03189796.