Departments of Radiology, Daejeon St. Mary’s Hospital, Medical School, The Catholic University of Korea, 520-2 Daeheung-Dong, Jung-Gu, Daejeon, Korea.
AJNR Am J Neuroradiol. 2010 Oct;31(9):1732-6. doi: 10.3174/ajnr.A2141. Epub 2010 Jul 1.
Thromboembolic events related to CAS continue to be the main limitation to the widespread use of this technique as a first-line treatment for carotid occlusive disease. Our aim was to evaluate thromboembolism during CAS using DWI for catheterization techniques of the carotid artery.
Thirty-two consecutive patients with symptomatic carotid stenosis underwent CAS involving 1 of 2 carotid artery catheterization techniques: One used a 7F or 8F catheter (group 1, n = 16) and the other used a coaxial system in which a 7F or 8F catheter was used in conjunction with a 4F or 5F catheter (group 2, n = 16). DWI was performed before and after CAS. Clinical variables, the number and location of NES on DWI after CAS, were compared between the 2 groups.
NES on DWI occurred in 53% of all patients. The incidence of NES was significantly higher in patients 65 years of age and older versus those younger than 65 years of age (P = .013). All NESs were asymptomatic, and their rate of occurrence did not differ significantly between groups 1 and 2. The incidence of NES in the other territories that were outside that of the treated carotid artery (P = .004) and the incidence of multiple NESs (P = .04) were significantly higher in group 1.
NES in the other territories mainly arises from the atherosclerotic aortic arch and arch vessels during the manipulation of endoluminal devices. The carotid artery catheterization technique using the coaxial system with a 7F or 8F catheter in conjunction with a 4F or 5F catheter reduced the incidence of NES in the other territories.
与颈动脉内膜切除术(CAS)相关的血栓栓塞事件仍然是限制该技术广泛应用于颈动脉闭塞性疾病一线治疗的主要因素。我们旨在评估使用 DWI 评估颈动脉血管介入技术过程中的血栓栓塞事件。
32 例有症状性颈动脉狭窄的患者接受了 CAS 治疗,涉及到 2 种颈动脉导管插入技术中的 1 种:1 种使用 7F 或 8F 导管(第 1 组,n=16),另 1 种使用同轴系统,其中 7F 或 8F 导管与 4F 或 5F 导管联合使用(第 2 组,n=16)。在 CAS 前后进行 DWI。比较两组患者的临床变量、CAS 后 DWI 上 NES 的数量和位置。
所有患者中有 53%出现 DWI 上的 NES。65 岁及以上患者 NES 的发生率明显高于 65 岁以下患者(P=0.013)。所有 NES 均为无症状,两组间 NES 的发生率无显著差异。在治疗颈动脉以外的其他部位(P=0.004)和多发性 NES(P=0.04)的发生率在第 1 组中明显更高。
其他部位的 NES 主要是在腔内器械操作过程中来源于粥样硬化的主动脉弓和弓部血管。使用同轴系统,7F 或 8F 导管与 4F 或 5F 导管联合的颈动脉导管插入技术可降低其他部位的 NES 发生率。