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生物可吸收固定术治疗不稳定剥脱性骨软骨炎病变。

Bioabsorbable fixation of unstable osteochondritis dissecans lesions.

机构信息

Mayo Clinic, Rochester, Minnesota 55905, USA.

出版信息

Am J Sports Med. 2010 Oct;38(10):2065-70. doi: 10.1177/0363546510371369. Epub 2010 Jul 1.

Abstract

BACKGROUND

Osteochondritis dissecans lesions of the knee in adult patients frequently require surgical intervention. However, the ideal method of osteochondral fragment fixation remains uncertain.

PURPOSE

This study was undertaken to determine the clinical, functional, and radiographic outcomes of bioabsorbable fixation for unstable osteochondritis dissecans lesions involving the femoral condyles of the knee in skeletally mature patients.

STUDY DESIGN

Case series; Level of evidence, 4.

METHODS

Skeletally mature patients with an unstable osteochondritis dissecans lesion of the femoral condyle (Ewing and Voto stages II-IV) treated with bioabsorbable internal fixation and minimum 1-year follow-up were included in this retrospective study cohort. Pre- and postoperative radiographs were reviewed and postoperative Lysholm and International Knee Documentation Committee (IKDC) scores were documented.

RESULTS

A total of 21 knees in 21 patients satisfied the inclusion criteria, and 3 patients were lost to follow-up. The remaining 18 patients were evaluated at a mean of 59 months after surgery (range, 12-154 months). The 14 male and 4 female patients had a mean age of 19 years at the time of surgery (range, 14-39 years). Ewing and Voto classification included 8 stage II lesions, 9 stage III lesions, and 1 stage IV lesion. Fragment fixation methods included bioabsorbable nails (11), pins (3), darts (2), screws (1), and combined screws and darts (1). Mean postoperative Lysholm and IKDC scores were 85 and 82, respectively. Fragment union occurred in 12 knees (67%); the remaining 6 knees (33%) required removal of the loose fragment. Of the 11 patients treated with bioabsorbable nails, 2 (18%) required reoperation for nail back-out.

CONCLUSION

The authors recommend caution when using bioabsorbable fixation for osteochondritis dissecans lesions in skeletally mature patients because of the low rate of clinical healing and high complication rate. Failure with unthreaded fixation devices may be caused by inadequate compression and not necessarily be related to bioabsorbability.

摘要

背景

成人膝关节剥脱性骨软骨炎病变常需手术干预,但骨软骨碎片固定的理想方法仍不确定。

目的

本研究旨在确定生物可吸收固定治疗成熟骨骼患者膝关节股骨髁不稳定剥脱性骨软骨炎病变的临床、功能和放射学结果。

研究设计

病例系列;证据水平,4 级。

方法

本回顾性研究队列纳入了接受生物可吸收内固定治疗且随访至少 1 年的不稳定股骨髁剥脱性骨软骨炎(Ewing 和 Voto 分期 II-IV)的成熟骨骼患者。回顾术前和术后 X 线片,并记录术后 Lysholm 和国际膝关节文献委员会(IKDC)评分。

结果

共 21 例患者的 21 个膝关节符合纳入标准,3 例失访。其余 18 例患者在术后平均 59 个月(12-154 个月)时进行评估。14 例男性和 4 例女性患者的手术时平均年龄为 19 岁(14-39 岁)。Ewing 和 Voto 分类包括 8 例 II 期病变、9 例 III 期病变和 1 例 IV 期病变。碎片固定方法包括生物可吸收钉(11 例)、针(3 例)、飞镖(2 例)、螺钉(1 例)和螺钉联合飞镖(1 例)。术后平均 Lysholm 和 IKDC 评分为 85 和 82。12 个膝关节(67%)发生碎片融合,其余 6 个膝关节(33%)需要取出游离碎片。11 例接受生物可吸收钉治疗的患者中,2 例(18%)因钉脱出而再次手术。

结论

作者建议在成熟骨骼患者中使用生物可吸收固定治疗剥脱性骨软骨炎病变时应谨慎,因为临床愈合率低,并发症发生率高。未螺纹固定装置失败可能是由于压缩不足引起的,不一定与可吸收性有关。

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