Webb Jonathan E, Lewallen Laura W, Christophersen Christy, Krych Aaron J, McIntosh Amy L
Orthopedics. 2013 Nov;36(11):e1444-9. doi: 10.3928/01477447-20131021-30.
Juvenile osteochondritis dissecans (OCD) lesions of the knee are a common cause of knee pain in skeletally immature patients.The authors sought to determine lesion healing rates, the risk factors associated with failure to heal, and the clinical outcomes for patients who underwent internal fixation for unstable OCD lesions. A retrospective review was conducted of all patients who underwent internal fixation of OCD lesions from 1999 to 2009. Using validated scoring systems, clinical outcome and functional activity were evaluated at the follow-up. The study group comprised 19 patients (20 knees). Mean patient age was 14.5 years (range, 12-17 years). Mean clinical follow-up was 7 years (range, 2-13 years). Mean radiographic follow-up was 2.5 years (range, 0.5-9 years). Fourteen (70%) lesions were grade 3 and 6 (30%) were grade 4. Eleven knees had lateral condyle lesions and 9 had medial lesions. Bioabsorbable fixation was used in 13 knees, metal fixation was used in 5 knees, and 2 knees were fixed with a combination of methods. Osseous integration was evident in 15 (75%) of 20 knees at final follow-up. The 5 unhealed lesions were lateral condylar lesions. Mean Tegner activity scores improved from 3.3 preoperatively to 5.6 at final follow-up. Mean Lysholm and International Knee Documentation Committee scores were 86.8 and 88.7, respectively, at final follow-up. Further operative intervention was required in 11 knees, with 50% of patients undergoing removal of hardware and 15% requiring subsequent osteochondral allograft transplantation. The authors recommend bioabsorbable fixation for symptomatic stable lesions and metal compression screws with staged removal for unstable lesions.
青少年膝关节剥脱性骨软骨炎(OCD)病变是骨骼未成熟患者膝关节疼痛的常见原因。作者试图确定病变的愈合率、不愈合的相关危险因素以及接受不稳定OCD病变内固定治疗患者的临床结局。对1999年至2009年期间接受OCD病变内固定治疗的所有患者进行了回顾性研究。使用经过验证的评分系统,在随访时评估临床结局和功能活动。研究组包括19例患者(20个膝关节)。患者平均年龄为14.5岁(范围12 - 17岁)。平均临床随访时间为7年(范围2 - 13年)。平均影像学随访时间为2.5年(范围0.5 - 9年)。14个(70%)病变为3级,6个(30%)为4级。11个膝关节有外侧髁病变,9个有内侧病变。13个膝关节使用了生物可吸收固定,5个膝关节使用了金属固定,2个膝关节采用了联合固定方法。在最后随访时,20个膝关节中有15个(75%)实现了骨整合。5个未愈合病变均为外侧髁病变。平均Tegner活动评分从术前的3.3提高到最后随访时的5.6。最后随访时,平均Lysholm评分和国际膝关节文献委员会评分分别为86.8和88.7。11个膝关节需要进一步手术干预,50%的患者接受了内固定取出术,15%的患者随后需要进行骨软骨异体移植。作者建议对有症状的稳定病变采用生物可吸收固定,对不稳定病变采用金属加压螺钉并分期取出。