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我们从北非癌症发病率的新数据中学到了什么?

[What are we learning from the new data on cancer incidence in North Africa].

作者信息

Sobrato Irene, Busso Paola, Zanetti Roberto

机构信息

Registro Tumori Piemonte, CPO, Torino.

出版信息

Epidemiol Prev. 2010 Jan-Apr;34(1-2):23-6.

Abstract

Over a period of a few years, Cancer registries in North Africa (Morocco, Algeria, Tunisia, Libya, Egypt) increased in number from one to seven. Currently they serve 9.7% of the total regional population. The pattern of risk presented by their data (which appear to be good enough, according to the available indicators) is unique. The total cancer burden in different North Africa countries is between one fourth and one half (on average one third) of the corresponding risk in Europe. The overall rate, age standardized on world population, ranges in men from 94.0/100,000 in Sètif, Algeria, to 162.9/100,000 in Garbiah, Egypt. Similar is the range of the risk between countries in women (from 84.7 and 164.0/100,000). The case mixing and the level of the site specific rates are quite homogeneous between the considered countries. The most frequent cancers are those observed in Europe (lung, breast, colon, prostate). This pattern completely differs from that of black Africa countries, where infection-related cancers predominate. The clinically well known excess risk for nasopharyngeal carcinoma in Maghrebi countries is confirmed and quantified by the presented data (with rates as high as 5.4/100,000 in men and 1.9/100,000 in women, ten times higher than in Europe).

摘要

在几年时间里,北非(摩洛哥、阿尔及利亚、突尼斯、利比亚、埃及)的癌症登记处数量从1个增加到了7个。目前,这些登记处覆盖了该地区总人口的9.7%。其数据呈现出的风险模式(根据现有指标来看似乎足够完善)很独特。北非不同国家的癌症总负担在欧洲相应风险的四分之一到二分之一之间(平均为三分之一)。以世界人口为标准进行年龄标准化后的总体发病率,男性范围从阿尔及利亚塞提夫的94.0/10万到埃及加比亚的162.9/10万。女性各国之间的风险范围也类似(从84.7到164.0/10万)。在所考虑的国家中,病例组合和特定部位发病率水平相当一致。最常见的癌症是在欧洲观察到的那些(肺癌、乳腺癌、结肠癌、前列腺癌)。这种模式与黑非洲国家完全不同,在黑非洲国家,与感染相关的癌症占主导。马格里布国家临床上众所周知的鼻咽癌额外风险通过所呈现的数据得到了证实和量化(男性发病率高达5.4/10万,女性为1.9/10万,比欧洲高十倍)。

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