[尸检材料中的酒精性脑病]
[Alcoholic encephalopathies in autopsy material].
作者信息
Riethdorf L, Warzok R, Schwesinger G
机构信息
Institut für Pathologische Anatomie, Ernst-Moritz-Arndt-Universität Greifswald, BRD.
出版信息
Zentralbl Pathol. 1991;137(1):48-56.
A report is given on incidence, complications, causes of death, and morphological diagnosis of chronic alcoholism in autopsy material. Chronic alcoholism was registered in 8.4% of all autopsies. The average age at death of alcoholics, particularly female, was significantly lower than that of all autopsy material. Pneumonia was the most frequent direct cause of death (21.1%). Acute ethanol intoxication was in second position (15.8%). Wernicke's encephalopathy was observed in 0.6% of all autopsies (18% of alcoholics), cerebellar atrophy occurred in 0.4% (12%), and central pontine myelinolysis was found in 0.2% (7%). The mean brain weight of alcoholics was 1310 g as compared with 1400 g of controls. Problems of clinical and postmortal diagnosis as well as medical and social consequences are discussed.
本文报告了尸检材料中慢性酒精中毒的发病率、并发症、死亡原因及形态学诊断。在所有尸检中，慢性酒精中毒的发生率为8.4%。酗酒者的平均死亡年龄，尤其是女性，显著低于所有尸检材料的平均死亡年龄。肺炎是最常见的直接死因（21.1%）。急性乙醇中毒位居第二（15.8%）。在所有尸检中，韦尼克脑病的发生率为0.6%（酗酒者中为18%），小脑萎缩发生率为0.4%（12%），脑桥中央髓鞘溶解症发生率为0.2%（7%）。酗酒者的平均脑重为1310克，而对照组为1400克。文中还讨论了临床和死后诊断问题以及医学和社会后果。
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