Jadotte Yuri T, Sarkissian Navér A, Kadire Helchem, Lambert W Clark
Eplasty. 2010 Jun 21;10:e46.
We present the case of a white man with a facial nodule suspicious for basal cell carcinoma.
Biopsy revealed clusters of basaloid tumor cells with peripheral palisading, consistent with a superficial spreading variant of basal cell carcinoma.
The patient was treated with Mohs micrographic surgery, with clear margins achieved after the second stage of excision. However, since it was a superficial spreading basal cell carcinoma, this was followed by topical imiquimod treatment.
Topical chemotherapy with imiquimod or 5-fluorouracil may be valuable alternatives or adjuncts, given the increased likelihood of recurrence after surgical excision of superficial spreading basal cell carcinoma. Mohs surgery is of limited value in the management of superficial spreading basal cell carcinoma because it characteristically shows areas of uninvolved skin between tumor nests.
我们报告一例面部有可疑基底细胞癌结节的白人男性病例。
活检显示基底样肿瘤细胞簇，周围有栅栏状排列，符合基底细胞癌的浅表扩散型。
患者接受了莫氏显微外科手术，在切除的第二阶段后切缘清晰。然而，由于这是一例浅表扩散型基底细胞癌，随后进行了咪喹莫特局部治疗。
鉴于浅表扩散型基底细胞癌手术切除后复发的可能性增加，咪喹莫特或5-氟尿嘧啶局部化疗可能是有价值的替代或辅助治疗方法。莫氏手术在浅表扩散型基底细胞癌的治疗中价值有限，因为其特征是肿瘤巢之间有未受累皮肤区域。
