首次使用两个摩尔当量的烯酮硅缩醛和一个摩尔当量的α,β-不饱和酯，在氢氧化钠催化剂作用下，通过 Mukaiyama-Michael 反应/交叉-Claisen 缩合的串联反应。
First sequential Mukaiyama-Michael reaction/crossed-Claisen condensation using two molar ketene silyl acetals and one molar alpha,beta-unsaturated esters promoted by a NaOH catalyst.
机构信息
Department of Chemistry, School of Science and Technology, Kwansei Gakuin University, 2-1 Gakuen, Sanda, Hyogo, 669-1337, Japan.
出版信息
Chem Commun (Camb). 2010 Aug 28;46(32):5930-2. doi: 10.1039/c0cc01110j. Epub 2010 Jul 2.
PMID:20596594
Abstract
The NaOH-catalyzed first sequential Mukaiyama-Michael reaction/crossed-Claisen condensation is developed using two molar ketene silyl acetals and one molar alpha,beta-unsaturated esters in either a stepwise or one-pot manner.
摘要
NaOH 催化的 Mukaiyama-Michael 反应/交叉-Claisen 缩合的首次连续反应，使用两摩尔酮烯醇硅缩醛和一摩尔α,β-不饱和酯，以分步或一锅法的方式进行。
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