不同结局测量指标对饮食障碍 3 年随访中缓解率评估的影响。
The impact of different outcome measures on estimates of remission in a 3-year follow-up of eating disorders.
机构信息
School of Health and Medical Sciences, Psychiatric Research Centre, Örebro University, Sweden.
出版信息
Eur Eat Disord Rev. 2011 Jan-Feb;19(1):2-11. doi: 10.1002/erv.1031.
OBJECTIVE
To examine the impact of using different outcome measures on estimates of remission rates in eating disorders (ED).
METHOD
Adult ED patients (n = 334) included in a naturalistic, longitudinal project were assessed 3 years after intake. Remission was operationally defined using six different measures of outcome. Pairwise analyses of agreement between outcome measures were also calculated.
RESULTS
Remission rates for the entire group varied considerably from 24.3 to 77.8% depending on how remission was defined and who made the assessment (experts or patients). Outcome measures performed differently depending on diagnosis, and agreement between measures varied from none to very good.
CONCLUSION
The impact of different definitions of outcome on remission estimates is considerable. There is a need to validate different estimates of remission by examining them in relation to multiple domains of outcome over time and by critically examining their relative merits both empirically and clinically.
目的
探讨使用不同结局测量指标对进食障碍（ED）缓解率估计的影响。
方法
纳入一项自然主义、纵向项目的成年 ED 患者（n=334），在入组后 3 年进行评估。使用六种不同的结局测量指标对缓解进行操作性定义。还计算了结局测量指标之间的一致性的两两分析。
结果
根据缓解的定义和评估者（专家或患者）的不同，整个组的缓解率差异很大，从 24.3%到 77.8%不等。结局测量指标的表现因诊断而异，且各指标之间的一致性从无到很好不等。
结论
不同结局定义对缓解估计的影响是相当大的。需要通过在一段时间内检查多个结局领域，以及从经验和临床角度批判性地检查它们的相对优点，来验证不同的缓解估计。
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