Department of Dermatology and Venereology, Al-Kuwait University Hospital, Sana'a University Medical School, Sana'a, Republic of Yemen.
Dermatol Ther. 2010 May-Jun;23(3):312-5. doi: 10.1111/j.1529-8019.2010.01330.x.
Four forms of calcinosis cutis exist: metastatic calcinosis, dystrophic calcinosis, idiopathic calcinosis, and subepidermal calcified nodules, usually referred to as cutaneous calculi because single, small, raised, hard nodules are present. Occasionally, there are two or three nodules, and in some instances there are numerous or even innumerable nodules. Most patients are children, but in some patients, a nodule is present already at birth or does not appear until about adult life; in some instances, the surface of the nodule is verrucous, but it may be smooth. The most common location of the nodule is the face. A 12-year-old Yemeni child patient presented with warty, hard- and smooth-surface, white, and small and large non-itchy numerous nodules in the face and in the four extremities, which started at 4 years after birth, of 8 years' duration. Serum levels of calcium, phosphorous, and parathyroid hormones were normal. Plain chest X-ray, abdominal ultrasonography, and complete blood count picture were normal. Skin biopsy followed by histopathological examination was diagnostic. The patient was treated with curettage and surgical removal.
转移性钙化、营养不良性钙化、特发性钙化和皮下钙化结节,通常称为皮肤结石,因为存在单个、小、凸起、坚硬的结节。偶尔有两个或三个结节,在某些情况下有许多甚至无数个结节。大多数患者为儿童,但在某些患者中,结节出生时即已存在,或直到成年后才出现;在某些情况下,结节表面呈疣状,但也可能光滑。结节最常见的部位是面部。一名 12 岁的也门儿童患者,面部和四肢出现疣状、坚硬而光滑表面、白色、大小不一、无瘙痒、众多的小结节,这些结节始于出生后 4 年,持续 8 年。血清钙、磷和甲状旁腺激素水平正常。胸部 X 线平片、腹部超声和全血细胞计数均正常。皮肤活检后组织病理学检查可确诊。患者接受了刮除术和手术切除治疗。