Zukowski A J, Nicolaides A N, Szendro G, Irvine A, Lewis R, Malouf G M, Hobbs J T, Dudley H A
Irvine Laboratory for Cardiovascular Investigation and Research, St. Mary's Hospital Medical School, London, UK.
Br J Surg. 1991 May;78(5):625-9. doi: 10.1002/bjs.1800780532.
A total of 149 consecutive unselected patients (221 limbs) who presented with signs and symptoms of chronic venous problems (varicose veins with or without ankle oedema, skin changes and leg ulcers) have been studied by clinical examination, ascending deep to superficial venography, Doppler ultrasound and ambulatory venous pressure measurements. Of the limbs, 180 (82 per cent) had varicose veins without obstruction in the deep veins or reflux in the popliteal or femoral veins while 41 (18 per cent) had deep venous disease. Of the 180 limbs with 'primary' varicose veins 110 (60 per cent) did not have incompetent calf perforating veins (group A) while 70 (40 per cent) did (group B). On the basis of the ambulatory venous pressure after calf muscle exercise and the refilling time, the incompetent calf perforating veins of limbs in group B belonged to three subgroups of different haemodynamic significance. In 20 limbs (30 per cent) they were found to be of no haemodynamic significance, in 25 (35 per cent) of moderate haemodynamic significance and in 25 (35 per cent) of major haemodynamic significance. The last were, on clinical examination, indistinguishable from limbs with deep venous disease although they had patent deep veins with competent popliteal valves.
共有149例连续入选的未经过筛选的患者(221条肢体)接受了研究,这些患者均有慢性静脉疾病的体征和症状(伴有或不伴有踝部水肿、皮肤改变和腿部溃疡的静脉曲张),研究方法包括临床检查、从深静脉到浅静脉的上行静脉造影、多普勒超声检查以及动态静脉压测量。在这些肢体中,180条(82%)有静脉曲张,深静脉无阻塞,腘静脉或股静脉无反流,而41条(18%)有深静脉疾病。在180条有“原发性”静脉曲张的肢体中,110条(60%)没有功能不全的小腿穿通静脉(A组),而70条(40%)有(B组)。根据小腿肌肉运动后的动态静脉压和再充盈时间,B组肢体中功能不全的小腿穿通静脉可分为具有不同血流动力学意义的三个亚组。在20条肢体(30%)中,发现它们无血流动力学意义;在25条(35%)中,具有中等血流动力学意义;在25条(35%)中,具有主要血流动力学意义。最后一组在临床检查中与有深静脉疾病的肢体无法区分,尽管它们的深静脉通畅,腘静脉瓣膜功能正常。