Department of Physical Therapy, Graduate School of Rehabilitation Science, Daegu University, Republic of Korea.
Neurosci Lett. 2010 Aug 30;481(1):51-3. doi: 10.1016/j.neulet.2010.06.052. Epub 2010 Jun 25.
The mammillothalamic tract (MTT) is a part of the Papez circuit and connects the mammillary body and anterior thalamus. No studies of the MTT have been performed using diffusion tensor tractography (DTT). In the current study, we attempted to identify the MTT in the human brain using DTT. We recruited 25 healthy volunteers for this study. Diffusion tensor images (DTIs) were scanned using 1.5-T, and the MTT was obtained using FMRIB software. Values of fractional anisotropy (FA), mean diffusicity (MD), and tract volume of the MTT were measured. The location of the highest probability point of the MTT was measured at the bicommissural level. MTTs of all subjects, which originated from the mammillary body, ascended posteriorly to the bicommissural level, along the third ventricle, and then ascended to the anterior thalamus in the antero-lateral direction. Average location of the MTT was 37.15% from the most posterior border of the anterior commissure to the most posterior border of the third ventricle at the bicommissural level. We identified the MTT in the human brain using DTT. These methods and results would be helpful to both clinicians and researchers in this field.
乳头丘脑束（MTT）是帕佩兹回路的一部分，连接着乳头体和前丘脑。目前还没有使用弥散张量纤维束成像（DTT）对 MTT 进行研究。在本研究中，我们试图使用 DTT 来识别人类大脑中的 MTT。我们招募了 25 名健康志愿者进行这项研究。使用 1.5-T 进行弥散张量成像（DTI）扫描，并使用 FMRIB 软件获得 MTT。测量 MTT 的各向异性分数（FA）、平均弥散度（MD）和束体积值。在联合间水平测量 MTT 的最高概率点的位置。所有受试者的 MTT 均起源于乳头体，向后沿第三脑室上升至联合间水平，然后沿前外侧方向上升至前丘脑。在联合间水平，MTT 位于前连合后缘至第三脑室后缘的 37.15%处。我们使用 DTT 在人类大脑中识别了 MTT。这些方法和结果将有助于该领域的临床医生和研究人员。
