Department of Psychology, University of British Columbia, Vancouver, BC, Canada.
Brain Behav Immun. 2010 Nov;24(8):1324-31. doi: 10.1016/j.bbi.2010.06.007. Epub 2010 Jun 25.
To test whether effects of socioeconomic environments can persist across generations, we examined whether parents' childhood socioeconomic status (SES) could predict blood pressure (BP) trajectories in their youth across a 12-month study period and C-reactive protein (CRP) levels at one year follow-up.
BP was assessed in 88 healthy youth (M age = 13 ± 2.4) at three study visits, each 6 months apart. CRP was also assessed in youth at baseline and one year follow-up. Parents reported on current and their own childhood SES (education and crowding).
If parents' childhood SES was lower, their children displayed increasing SBP and CRP over the 12-month period, or conversely, the higher parents' childhood SES, the greater the decrease in SBP and CRP in their youth over time. These effects persisted even after controlling for current SES. A number of other factors, including child health behaviors, parent psychosocial characteristics, general family functioning, and parent physiology could not explain these effects.
Our study suggests that the SES environment parents grow up in may influence physical health across generations, here, SBP and CRP in their children, and hence that intergenerational histories are important to consider in predicting cardiovascular health in youth.
为了检验社会经济环境的影响是否能够跨代持续,我们研究了父母在儿童时期的社会经济地位(SES)是否能够预测其在青年时期的血压(BP)轨迹,研究时间跨度为 12 个月,并预测一年后的 C 反应蛋白(CRP)水平。
在三次研究访问中,每 6 个月一次,评估了 88 名健康青年(M 年龄=13±2.4 岁)的血压。在基线和一年随访时,还评估了 CRP。父母报告了当前和自己儿童时期的 SES(教育和拥挤程度)。
如果父母的儿童时期 SES 较低,他们的孩子在 12 个月的时间内 SBP 和 CRP 会逐渐升高,或者相反,如果父母的儿童时期 SES 较高,他们的孩子的 SBP 和 CRP 随着时间的推移会逐渐下降。即使控制了当前的 SES,这些影响仍然存在。其他一些因素,包括儿童健康行为、父母的心理社会特征、一般家庭功能和父母的生理状况,都无法解释这些影响。
我们的研究表明,父母成长的 SES 环境可能会影响跨代的身体健康,在这里是指他们孩子的 SBP 和 CRP,因此,代际历史在预测青年心血管健康方面是很重要的。