García-Bocanegra Ignacio, Simon-Grifé Meritxell, Dubey Jitender P, Casal Jordi, Martín Gerard E, Cabezón Oscar, Perea Anselmo, Almería Sonia
Departamento de Sanidad Animal, Facultad de Veterinaria, UCO, Campus Universitarios de Rabanales, Apdo., Córdoba, Spain.
Parasitol Int. 2010 Sep;59(3):421-6. doi: 10.1016/j.parint.2010.06.001. Epub 2010 Jun 18.
Serum samples from 2970 (1400 sows, 1570 fattening) pigs, from 100 farms in the 10 main swine production regions in Spain were tested for antibodies against T. gondii by the modified agglutination test (MAT). Antibodies to T. gondii (MAT 1:25 or higher) were detected in 492 pigs (16.6%, 9.7% in fattening pigs and 24.2% in sows). The herd prevalence was 85.0% (95% CI: 78-92) and within-farm prevalence ranged from 2.9% to 92.8% (median=17.6%). Statistically significant differences were observed among sampling regions with seroprevalence significantly higher in pigs from Valencia Community (27.3%), Extremadura (23.3%) and Catalonia (21.2%). A generalized estimating equations model indicated that the risk factors associated with T. gondii seroprevalence were: age, sows compared to fattening pigs (OR=2.9; 95% CI=1.83-4.53), lack of rodent control (OR=1.9; 95% CI=1.04-3.60) and presence of cats (OR=1.6; 95% CI=1.12-2.34). The seroprevalence observed in the present study indicates a widespread, although variable, exposure to T. gondii among domestic pigs in Spain, which might have important implications for public health. Management measures including control of rodents and cats on the farms could help to reduce the observed prevalence levels in Spain.
对来自西班牙10个主要生猪产区100个农场的2970头猪（1400头母猪、1570头育肥猪）的血清样本进行改良凝集试验（MAT），检测抗弓形虫抗体。在492头猪中检测到抗弓形虫抗体（MAT 1:25或更高）（16.6%，育肥猪中为9.7%，母猪中为24.2%）。猪群流行率为85.0%（95%CI：78 - 92），农场内流行率在2.9%至92.8%之间（中位数 = 17.6%）。在采样地区之间观察到统计学上的显著差异，巴伦西亚自治区（27.3%）、埃斯特雷马杜拉（23.3%）和加泰罗尼亚（21.2%）的猪血清阳性率显著更高。广义估计方程模型表明，与弓形虫血清阳性率相关的风险因素为：年龄，母猪与育肥猪相比（OR = 2.9；95%CI = 1.83 - 4.53），缺乏鼠类控制（OR = 1.9；95%CI = 1.04 - 3.60）和有猫存在（OR = 1.6；95%CI = 1.12 - 2.34）。本研究中观察到的血清阳性率表明，西班牙家猪中弓形虫感染虽然存在差异但广泛存在，这可能对公共卫生有重要影响。包括控制农场鼠类和猫在内的管理措施有助于降低西班牙观察到的流行率水平。
