Bone Density Research Laboratory, Department of Health and Exercise Science, University of Oklahoma, Norman, OK 73019, USA.
Bone. 2010 Sep;47(3):650-6. doi: 10.1016/j.bone.2010.06.019. Epub 2010 Jun 25.
Whole-body vibration (WBV) has been shown to be osteogenic in animal models; however, its application in humans is not clear. The purpose of this study was to examine the effects of an 8-month program involving WBV plus resistance training on bone mineral density (BMD) and bone metabolism in older postmenopausal women. Fifty-five estrogen-deficient postmenopausal women were assigned to a resistance training group (R, n=22), a WBV plus resistance training group (WBVR, n=21), or a control group (CON, n=12). R and WBVR performed upper and lower body resistance exercises 3 days/week at 80% 1 Repetition Maximum (1RM). WBVR received vibration (30-40 Hz, 2-2.8 g) in three different positions preceding the resistance exercises. Daily calcium intake, bone markers (Bone alkaline phosphatase (Bone ALP); C-terminal telopeptide of Type I collagen (CTX), and BMD of the spine, dual femur, forearm, and total body (DXA) were measured at baseline and after the intervention. At baseline, there were no significant group differences in strength, BMD, or bone marker variables. After 8 months of R or WBVR, there were no significant group or time effects in Bone ALP, CTX, or total body, spine, left hip or right trochanter BMD. However, right total hip and right femoral neck BMD significantly (p<0.05) decreased in all groups. A group x time interaction (p<0.05) was detected at radius 33% BMD site, with CON slightly increasing, and WBVR slightly decreasing. R and WBVR significantly (p<0.05) increased 1RM strength for all exercises, while CON generally maintained strength. WBVR had significantly (p<0.05) greater percent increases in muscular strength than R at 4 months for lat pull down, seated row, hip abduction and hip adduction and at 8 months for lat pull down, hip abduction and hip adduction. Bone metabolism in postmenopausal women was not affected by resistance training either with or without WBV. In contrast, the addition of WBV augmented the positive effects of resistance training on muscular strength in these older women.
全身振动 (WBV) 已被证明在动物模型中具有成骨作用；然而，其在人类中的应用尚不清楚。本研究的目的是探讨为期 8 个月的全身振动联合抗阻训练对绝经后老年女性骨密度 (BMD) 和骨代谢的影响。将 55 名雌激素缺乏的绝经后妇女分为抗阻训练组 (R，n=22)、全身振动联合抗阻训练组 (WBVR，n=21) 和对照组 (CON，n=12)。R 和 WBVR 每周进行 3 天的上下肢抗阻训练，强度为 80% 1 重复最大强度 (1RM)。WBVR 在抗阻训练前的三个不同位置接受振动 (30-40 Hz，2-2.8 g)。在基线和干预后测量每日钙摄入量、骨标志物 (骨碱性磷酸酶 (Bone ALP)；I 型胶原 C 端肽 (CTX) 和脊柱、双侧股骨、前臂和全身 (DXA) 的 BMD。在基线时，各组间在力量、BMD 或骨标志物变量方面无显著差异。经过 8 个月的 R 或 WBVR 治疗后，各组间在 Bone ALP、CTX 或全身、脊柱、左侧髋部或右侧转子间 BMD 方面均无显著的组间或时间效应。然而，所有组的右侧总髋部和右侧股骨颈 BMD 均显著下降 (p<0.05)。在桡骨 33% BMD 部位检测到组间时间交互作用 (p<0.05)，CON 略有增加，WBVR 略有减少。R 和 WBVR 显著增加了所有运动的 1RM 力量 (p<0.05)，而 CON 通常保持力量。WBVR 在 4 个月时的 Lat Pull Down、Seated Row、髋外展和髋内收以及 8 个月时的 Lat Pull Down、髋外展和髋内收运动中，肌肉力量的百分比增加显著大于 R (p<0.05)。抗阻训练无论是否联合 WBV 对绝经后妇女的骨代谢均无影响。相比之下，在这些老年女性中，全身振动联合抗阻训练增加了抗阻训练对肌肉力量的积极影响。
