Department of Orthopedic Surgery 357, Radboud University Nijmegen Medical Centre, PO Box 9101, Nijmegen 6500 HB, The Netherlands.
J Neurol Neurosurg Psychiatry. 2011 Mar;82(3):353-4. doi: 10.1136/jnnp.2009.191312. Epub 2010 Jul 2.
A 26-year-old man developed a movement disorder characterised by bradyphrenia, bradykinesia, rigidity, tremor and dystonia, several years after having been shot by a gun in the hip. Laboratory investigations revealed anaemia and porphyria. The authors demonstrate that his neurological condition was a delayed manifestation of lead toxicity, caused by slow absorption of lead from persisting bullet fragments in the hip joint. Treatment with excision of the femoral head and debridement of the hip followed by a total hip, in combination with chelating therapy, led to a remarkable remission.
一位 26 岁男性在臀部被枪击中数年后出现了运动障碍,其特征为智力迟钝、运动迟缓、僵硬、震颤和肌张力障碍。实验室检查发现贫血和卟啉症。作者表明,他的神经状况是由于髋关节中持续存在的弹片缓慢吸收铅而导致的铅中毒的延迟表现。通过切除股骨头和髋关节清创术,然后进行全髋关节置换术,并结合螯合疗法,患者的病情显著缓解。