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鼻唇瓣修复癌症患者口腔缺损的批判性评价

Critical appraisal of nasolabial flap for reconstruction of oral cavity defects in cancer patients.

作者信息

Mebeed Ali H, Hussein Hesham A, Saber Tarek Kh

机构信息

The Departments of Surgical Oncology , National Cancer Institute, Cairo University.

出版信息

J Egypt Natl Canc Inst. 2009 Mar;21(1):33-42.

PMID:20601969
Abstract

PURPOSE

Re-evaluation of nasolabial flap in lip and oral cavity reconstruction and role of each of its variants in reconstructing various intermediate size defects was addressed.

PATIENTS AND METHODS

Case-series study was conducted in National Cancer Institute, Cairo University over the period from July 2005 - January 2009 which included 23 patients with clinically T-1 N0, T-2 N0 invasive squamous cell carcinoma of buccal mucosa and the vermilion border of the lower lip. Immediately after surgical excision, one stage reconstruction of the defect was done using a type of nasolabial flap. All patients were followed and the median follow-up period was 7.5 month.

RESULTS

Twelve patients with the lower lip carcinoma and 11 patients with the carcinoma of buccal mucosa underwent surgical excision under frozen section control. 19 fasciocutaneous nasolabial flap and 4 facial artery musculomucosal flaps were used for reconstruction. Minor wound complications occurred in 2 flaps and one patient required secondary suture. Flap viability was reliable and was not affected by performance of a synchronous neck dissection. Functional results were satisfactory, cosmetic results were good in most of the patients and excellent when facial artery musculomucosal flap was used.

CONCLUSIONS

The nasolabial flap is a reliable and minimally traumatic local flap for one stage reconstruction of medium size defects in the oral cavity. The abundant blood supply allowed its modification in order to cover larger defects or to obtain better cosmetic results. This versatility makes it more widely used thus minimizing the use of local tongue flaps and split thickness grafts for covering these medium size defects in cases of buccal mucosa cancer or affecting the other lip or commissure in cases of lip cancer. It has a high viability rate, low complication rate; it is quick and easy to perform in addition to its satisfactory functional and cosmetic results.

KEY WORDS

Nasolabial flap (NLF) - Facial artery musculomucosal (FAMM) flap - Reconstruction of oral cavity - Squamous cell carcinoma (SCC) - Buccal mucosa - Lower lip reconstruction.

摘要

目的

重新评估鼻唇瓣在唇部和口腔重建中的应用,以及其各变体在修复各种中等大小缺损中的作用。

患者与方法

2005年7月至2009年1月在开罗大学国家癌症研究所进行了病例系列研究,纳入23例临床诊断为T-1 N0、T-2 N0的颊黏膜及下唇唇红缘浸润性鳞状细胞癌患者。手术切除后立即使用一种鼻唇瓣进行缺损的一期修复。对所有患者进行随访,中位随访期为7.5个月。

结果

12例下唇癌患者和11例颊黏膜癌患者在冰冻切片控制下接受了手术切除。使用了19个筋膜皮瓣鼻唇瓣和4个面动脉肌黏膜瓣进行重建。2个皮瓣出现轻微伤口并发症,1例患者需要二次缝合。皮瓣存活率可靠,不受同期颈部清扫术的影响。功能结果令人满意,大多数患者的美容效果良好,使用面动脉肌黏膜瓣时美容效果极佳。

结论

鼻唇瓣是一种可靠且创伤极小的局部皮瓣,可用于口腔中等大小缺损的一期修复。其丰富的血供使其能够进行改良,以覆盖更大的缺损或获得更好的美容效果。这种多功能性使其得到更广泛的应用,从而减少了在颊黏膜癌病例中使用局部舌瓣和中厚皮片来覆盖这些中等大小缺损的情况,以及在唇癌病例中影响另一侧唇或口角时的使用。它具有高存活率、低并发症发生率;操作快速简便,此外其功能和美容效果令人满意。

关键词

鼻唇瓣(NLF);面动脉肌黏膜(FAMM)瓣;口腔重建;鳞状细胞癌(SCC);颊黏膜;下唇重建

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